Inhibition of acyl-CoA hydrolase activity in liver microsomes by lysophospholipids. Biochem Biophys Res Commun 94: 1278–1284, 1980.Sun, G. Y., R. E. Smith, K. Chan, and R. MacQuarrie. 1980. Inhibition of acyl-CoA hydrolase activity in liver microsomes by lyso-phospholipids.Biochem. ...
Palmitic acid could not replace palmitoyl-CoA as the co-substrate indicating that the enzyme involved is an acyl-CoA: ecdysone acyltransferase and not a hydrolase. Formation of ecdysone-palmitate was maximal at 150–200 μM palmitoyl-CoA and was linear with time for up to 1 h. The enzyme ...
polifungini was found to be associated with the antibiotic-synthesizing ability, and was negatively correlated with both the thio-esterase activity (acetyl-CoA hydrolase, EC 3.1.2.1) and its affinity towards acetyl-CoA and propionyl-CoA. The apparent Michaelis constants with acetyl-CoA and ...
Berge RK, Flatmark T, Osmundsen H: Enhancement of long-chain acyl-CoA hydrolase activity in peroxisomes and mitochon-dria of rat liver by peroxisome proliferators. Eur J Biochem 141: 673–644, 1984 Article Google Scholar Mikkelsen J, Højrup P, Nielsen PF, Roepstorff P, Knudsen J: ...
ACOTs are divided into two families, named the Type-I and Type-II thioesterases, where the Type-I thioesterases, together with the acyltransferases, show a high degree of sequence similarity and structurally belong to the α/β-hydrolase superfamily, which is one of the largest superfamilies of...
基因全名 Cytosolic acyl coenzyme A thioester hydrolase 蛋白功能 Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoA...
for [尾-oxidation of CoAactivated intermediates, thioesterase, and lactone hydrolase, as well as completely unknown enzymes belonging to new protein families... Gescher,Johannes,Zaar,... - 《Journal of Bacteriology》 被引量: 147发表: 2002年 Characterization of acyl-CoA thioesterase activity in is...
基因全名Cytosolic acyl coenzyme A thioester hydrolase 蛋白功能Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH...
ACOT7 is a cytosolic acyl coenzyme A thioester hydrolase that primarily hydrolyzes the CoA thioester of palmitoyl-CoA. To determine whether or not ACOT7 depletion-mediated cytostasis is due to acyl-CoA thioesterase activity per se, we treated MCF7 cells with nordihydroguaiaretic acid (NDGA), ...
1.The following indexes were examined,such as the contents of TC,TG,LDL-C and HDL-C in serum;the contents of TC and TG,the activities of carnitine palmitoyl transterase-1(CPT-1),peroxisomal β-oxidation enzymes(POE) and phosphatidic acid phophyhydrolase(PAP) in liver;the excurrent content...