...生丙二醯基辅脢A(Malonyl-CoA), 进入脂肪合成作用(fatty acid synthesis), 形成脂肪。 disp.cc|基于4个网页 3. 脂酸合成 下载_0KB_ ... fatty acid peroxidase 脂[肪]酸过氧化酶fatty acid synthesis脂[肪]酸合成fatty acyl carnitine 脂醯肉硷 ... ...
Fatty acid synthesis involves the de novo assembly of acetate into saturated fatty acids as well as the desaturation and elongation of the dietary essential fatty acids – linoleic acid (C18:2n-6) and α-linolenic acid (C18:3n-3) – to highly unsaturated 20- and 22-carbon fatty acids essen...
Cancer cells need to adapt their metabolic state to different microenvironments, particularly during metastatic spread, when they are exposed to the circulatory system as well as the distant organ. Two studies now show that upregulation of fatty acid synthesis is required for the formation of breast...
下面附了一个review--‘The multifaceted roles of fatty acid synthesis in cancer’(Rohrig & Schulze, 2016) Summary of citrate export from the mitochondrial matrix and subsequent cytosolic fatty acid synthesis "Lipid metabolism, in particular the synthesis of fatty acids (FAs), is an essential cellul...
Fatty Acid Synthesis:脂肪酸的合成肪,合成,Fatty,Acid,fatty,acid,脂肪酸合成,脂肪酸的,脂肪酸,合成脂肪酸 文档格式: .ppt 文档大小: 10.07M 文档页数: 86页 顶/踩数: 0/0 收藏人数: 1 评论次数: 0 文档热度: 文档分类: 论文--毕业论文 文档标签: ...
the fatty acid synthesis are covalently linked allowing the translocation of the growing fatty acyl chain from one FAS enzymatic subunit to the next in a predetermined sequence that elongates the fatty acid by two carbons for each cycle, leading ultimately to a 16-carbon long-chain fatty acid. ...
Inhibitors of the lipogenic enzyme fatty acid synthase (FASN) have attracted much attention in the last decade as potential targeted cancer therapies. However, little is known about the molecular determinants of cancer cell sensitivity to FASN inhibitors (FASNis), which is a major roadblock to thei...
结果表明了miR-140是TGFA的上游调控因子,miR-140能抑制(P < 0.01)牛乳腺上皮细胞(BMECs)和甘油三酯(TAGs)产生;相反,TGFA促进(P < 0.01)不饱和脂肪酸和TAG生成。拯救实验进一步表明了miR-140/TGFA调控机制。综上所述,这些结果表明了miR-140/TGFA通路可以抑制(P < 0.01)奶牛乳腺上皮细胞中的乳脂代谢的进行,...
Adipocytes are the primary sites for fatty acid storage, but the synthesis rate of fatty acids is very low. The physiological significance of this phenomenon remains unclear. Here, we show that surplus fatty acid synthesis in adipocytes induces necroptos
Previous studies suggested that T helper type (Th)1 and Th17 cells depend on de novo fatty acid (FA) synthesis for their development and effector function. Here, we report that T-cell-specific targeting of the enzyme acetyl-CoA carboxylase 1 (ACC1), a major checkpoint controlling FA ...