Essential fatty acid synthesis and its regulation in mammals. Prostaglandins Leukot Essent Fatty Ac- ids. 2003; 68(2): 145-50.Nakamura MT, Nara TY (2003) Essential fatty acid synthesis and its regulation in mammals. Prostaglandins Leukot Essent Fatty Acids 68:145-150...
C. Joshi, Fatty acid synthesis and its regulation. Annu. Rev. Biochem. 52, 537 (1983). © 1983 by Annual Reviews Inc.] The assembly of rat liver FAS involves three stages: synthesis of the multifunctional polypeptide chains, formation of the dimer, and attachment of a 4’-phosphopante...
Annual Review of BiochemistryWakil, S. J., Stoops, J. K. and Joshi, V. C. (1983). Fatty acid synyhesis and its regulation. Annu. Rev. Biochem. 52:537-579Wakil SJ, Stoops JK, Joshi VC. 19...
Wakil SJ, Stoops JK, Joshi VC: Fatty acid synthesis and its regulation. Annu Rev Biochem. 1983, 52 (1): 537-579. 10.1146/annurev.bi.52.070183.002541. Article CAS PubMed Google Scholar Matsuzaka T, Shimano H, Yahagi N, Kato T, Atsumi A, Yamamoto T, Inoue N, Ishikawa M, Okada S...
coli and its regulation, and it provides the connection towards the production of fatty acids and related biofuels. The second part gives an overview about the achievements by genetic engineering of the fatty acid biosynthesis towards the production of next generation biofuels. Finally, the actual ...
In lactating rat mammary gland the activities of both enzymes are profoundly inhibited by starvation and rapidly re-activated (within 3 hours) upon refeeding. Unexpectedly during these dietary manipulations the rate of fatty acid synthesis can be more closely correlated with PDH than ACC even though...
Fatty acid synthesisInhalation exposureElevated airborne PCB levels in older schools are concerning due to their health impacts, including cancer, metabolic dysfunction-associated steatotic liver disease (MASLD), cardiovascular issues, neurodevelopmental diseases, and diabetes. During a four-week inhalation ...
TH17 and Treg cell development are reciprocally regulated by de novo fatty acid synthesis, and inhibition of acetyl-CoA carboxylase 1 (ACC1) attenuates TH17 cell–mediated autoimmune disease. Interleukin-17 (IL-17)-secreting T cells of the T helper 17 (T
结果表明了miR-140是TGFA的上游调控因子,miR-140能抑制(P < 0.01)牛乳腺上皮细胞(BMECs)和甘油三酯(TAGs)产生;相反,TGFA促进(P < 0.01)不饱和脂肪酸和TAG生成。拯救实验进一步表明了miR-140/TGFA调控机制。综上所述,这些结果表明了miR-140/TGFA通路可以抑制(P < 0.01)奶牛乳腺上皮细胞中的乳脂代谢的进行,...
Upregulation of fatty acid synthase (FASN) is a common event in cancer, although its mechanistic and potential therapeutic roles are not completely understood. In this study, we establish a key role of FASN during transformation. FASN is required for eliciting the anaplerotic shift of the Krebs...