Inhibitors of the lipogenic enzyme fatty acid synthase (FASN) have attracted much attention in the last decade as potential targeted cancer therapies. However, little is known about the molecular determinants of cancer cell sensitivity to FASN inhibitors (FASNis), which is a major roadblock to thei...
The regulation of fatty acid synthase (FAS) expression by sterols in a cultured human hepatoblastoma cell line, Hep G2, was studied. When cells were treated with compactin in a medium containing lipoprotein deficient serum, FAS mRNA level increased 1.6-fold. A squalene synthase inhibitor, TAN...
Fatty acid synthase (Fasn) is the key metabolic enzyme that accounts for the terminal catalytic step in fatty acid synthesis, which is hyperactivated in various tumors. In this study, we depicted that Fasn expression was elevated in human colorectal cancer (CRC), which accordingly led to lymphat...
Expression of fatty acid synthase is regulated by PGC‑1α and contributes to increased cell proliferation Expression of fatty acid synthase is regulated by PGC1α and contributes to increased cell proliferation.doi:10.3892/or.2017.6044proliferation... SH Yun,SW Shin,JI Park - 《Oncology Reports》...
fatty acid synthase [ˈfæti: ˈæsid ˈsinθeis] 释义 [医]脂肪酸合酶 行业词典 医学 〔EC 2.3.1.85〕脂肪酸合酶:催化长链脂肪酸合成的一种酶复合体。其反应式为乙酰CoA+n丙二酰CoA+2nNADPH→长链脂肪酸阴离子+nCO 2+2nNADPH+(NH)。哺乳类肝酶复合体先处理的产品是软脂酸CoA。脂肪酸合酶...
Fatty acid synthase (FAS) is a multienzyme complex that catalyses a sequence of reactions in each cycle of which a fatty acid is lengthened by two carbon atoms. From: Brewing: Science and Practice, 2004 About this pageAdd to MendeleySet alert ...
脂肪酸合成酶系统(fatty acid synthase system) 相关知识点: 试题来源: 解析 脂肪酸合酶系统:脂肪酸合酶系统包括酰基载体蛋白(ACP)和6种酶,它们分别是:乙酰转酰酶;丙二酸单酰转酰酶;β-酮脂酰ACP合成酶;β-酮脂酰ACP还原酶;β-羟;脂酰ACP脱水酶;烯脂酰ACP还原酶。反馈 收藏 ...
脂肪酸合成酶(Fatty acid synthase)脂肪酸合成酶脂肪酸合成酶 fatty acid synthetase 乙酰coa+7丙 = 酸coa+14nadph+14h + →棕榈酸 + 7co2+ 8coa + 14nadp + + 6h2o.催化上述反应的酶称为脂肪酸合成酶, 不过酵母酶的最终产物是棕榈酸coa.如图所示, 在丙二酸基和乙酰基缩合时, 在每次延长c2单位的同时...
脂肪酸合成酶(Fatty acid synthase)脂肪酸合成酶脂肪酸合成酶 fatty acid synthetase 乙酰coa+7丙 = 酸coa+14nadph+14h + →棕榈酸 + 7co2+ 8coa + 14nadp + + 6h2o.催化上述反应的酶称为脂肪酸合成酶, 不过酵母酶的最终产物是棕榈酸coa.如图所示, 在丙二酸基和乙酰基缩合时, 在每次延长c2单位的同时...
产品名称 细胞脂肪酸合成酶(fattyacidsynthase)活性比色法定量检测试剂盒 产品规格 20次 有效成分含量 99 检测方法 比色法 样本 组织,细胞,线粒体,细菌等 保质期 6个月 标记物 粪便 储存条件 冷藏或-20℃ 用途范围 仅用于科学实验研究使用 是否进口 否 包装规格 盒装 运输 快递发货 产地 上海 ...