This chapter describes the purification procedure of fatty acid ω-hydroxylase (alkane hydroxylase) from Pseudomonas oleovorans. The hydroxylation system induced in Pseudomonas oleovorans by growth on alkanes contains three proteins: NADH-rubredoxin reductase—a flavoprotein containing one molecule of flav...
We have examined in detail the substrate specificity of a rabbit kidney fatty acid omega-hydroxylase, designated cytochrome P-450ka2 (CYP4A7). The hydroxylation products were identified as omega- and (omega - 1)-hydroxy fatty acids mainly using gas chromatography-electron impact mass spectrometry....
fatty acid Thesaurus Medical Acronyms Encyclopedia Wikipedia Related to fatty acid:saturated fatty acid,Omega 3 fatty acid fatty acid n. Any of a large group of monoprotic acids, especially those found in animal and vegetable fats and oils, having the general formula CnH2n+1COOH. Characteristical...
This study demonstrates some variability in suberin amount and composition along the root axis and indicates the importance of omega-hydroxylation for suberin biosynthesis. Using reverse genetics, the cytochrome P450 fatty acid omega-hydroxylase CYP86A1 (At5g58860) has been identified as a key ...
The Arabidopsis cytochrome P450 CYP86A1 encodes a fatty acid omega -hydroxylase involved in suberin monomer biosynthesisHoferR.BriesenI.BeckM.PinotF.SchreiberL.ingentaconnectJOURNAL OF EXPERIMENTAL BOTANYR. Ho¨ fer, I. Briesen, M. Beck, F. Pinot, L. Schreiber, R. Franke, The Arabidopsis ...
Höfer, R. et al. TheArabidopsiscytochrome P450CYP86A1encodes a fatty acid omega-hydroxylase involved in suberin monomer biosynthesis.J. Exp. Bot.59, 2347–2360 (2008). ArticlePubMedPubMed CentralCASGoogle Scholar Beisson, F., Li-Beisson, Y., Bonaventure, G., Pollard, M. & Ohlrogge...
The induction of liver cytochrome P450 4A-catalyzed fatty acid omega-hydroxylase activity by clofibrate and other peroxisome proliferators has been propose... SS Sundseth,DJ Waxman - 《J.biol.chem》 被引量: 432发表: 1992年 Effects of Fatty Acids and Ketone Bodies on Cytochromes P450 2B, 4A...
As previously mentioned, omega-oxidation, the third and final fatty acid oxidation pathway, occurs in the endoplasmic reticulum. This pathway exists to process large, water-insoluble fatty acids that would otherwise be toxic to the cell in higher concentrations. Further details and mechanisms of thes...
Fatty acidhydroxylaseis required for the formation of 2-hydroxy fatty acids(hFA) (Alderson et al., 2004; Eckhardt et al., 2005), which are among the most important building blocks ofsphingolipidsin mammals (for review seeHama, 2010). Based on this it is likely that mutations inFA2Haffect...
In many of the above pathways, a particular group of fatty acids are especially potent, the n−3 (or omega-3) fatty acids. n−3 FATTY ACIDS A growing body of epidemiologic and experimental studies indicates that increased n−3 fatty acid consumption ameliorates or decreases the risk of...