fatty acid metabolism. Peroxisome proliferator-activated receptors (PPARs), for example, are ligand-activated transcription factors that regulate the expression of fatty acid oxidation genes. Sterol regulatory element-binding proteins (SREBPs) regulate gene expression in fatty acid production and absorption...
Fatty acid metabolisminvolves the conversion ofsucrose, a product ofphotosynthesis, into TAGs. The pathway starts in theplastidwhere fatty acid chains are elongated while conjugated toacyl carrier proteins(ACP) and ends in theendoplasmic reticulum(ER) where acyl CoAs are converted to diacylgrycerol ...
Fatty acid metabolism Fatty acid chains are polymerized in the cytoplasm and oxidized in themitochondrial matrix. This prevents competing side reactions between pathway intermediates and allows separate regulation of both pathways. However, since the precursor forfat synthesis, acetyl-coenzyme A (CoA), ...
Fatty acid metabolism内分泌关键词: 内分泌 临床研究术语 生化反应 词汇介绍 拓展阅读解析 fatty 英/ˈfæti/ 美 /ˈfæti/ 释义adj. 脂肪的;肥胖的;多脂肪的;脂肪过多的 n. 胖子 例句Moreover, brain tissue contains a great deal of oxidisable material, particularly in the fatty membranes...
Cardiac fatty acid metabolism and the induction of apoptosis. Fatty acids are the primary source of energy in the adult heart. Recently, however, it was discovered that certain saturated fatty acids, such as palmitate... GC Sparagna,DL Hickson-Bick - 《American Journal of the Medical Sciences》...
ACSL4 reprograms fatty acid metabolism in hepatocellular carcinoma via c-Myc/SREBP1 pathway 来自 Elsevier 喜欢 0 阅读量: 247 作者:JCABC D,CDA B,YCABC D,WH A,CY A,CP A,XF A,QC A,WW A,YL A 摘要: Lipid metabolic reprogramming plays a pivotal role in hepatocellular carcinoma (HCC) ...
The importance of fatty acid (FA) metabolism in cancer is well-established, yet the mechanisms underlying metabolic reprogramming remain elusive. Here, we identify tetraspanin CD37, a prognostic marker for aggressive B-cell lymphoma, as essential membran
A common feature of cancer cells is their ability to rewire their metabolism to sustain the production of ATP and macromolecules needed for cell growth, division and survival. In particular, the importance of altered fatty acid metabolism in cancer has received renewed interest as, aside their prin...
脂肪酸代谢PCR芯片 Fatty Acid Metabolism PCR Array 联系购买 配送服务: 运费￥0.00 数量: (库存9999件) 产品详细 地区:上海i 简介:上海 提供商:SABio 服务名称:PCR芯片 脂肪酸代谢PCR芯片可用于研究参与脂肪酸代谢的调控和酶通路的84个关键基因的表达。细胞,尤其是骨骼肌和脂肪组织中的细胞,主要以三酸甘油酯的...
In cancer cells, ATP-citrate lyase (ACLY), acetyl-CoA carboxylase (ACC), fatty acid synthase (FASN) and stearoyl-CoA desaturase (SCD) are considered the key enzymes involved in the metabolism of fatty acids [[9], [10], [11]]. These key lipogenic enzymes are upregulated in several ...