cells were "angiogenic adipocytes," which carried proteins usually used to promote blood vessel formation; "immune-related adipocytes," which make proteins related to immune cell functions; and "extracellular matrix adipocytes," which are related to scaffold proteins that help support cells' structures...
Nguyen, who is the first author of the paper, used CRISPR to activate genes that are dormant in white fat cells but are active in brown fat cells, in the hopes of finding the ones that would transform the white fat cells into the hungriest of beige fat cells. A gene called UCP1 rose...
So you don't actually "lose" fat cells, you "shrink" or "empty out" fat cells. Since fat cells can not only get bigger, but also multiply, you have be diligent and consistent in your fat-burning lifestyle because even after you shrink your fat cells, the cells are still there (in...
The team reports that type I interferons, a class of substances produced byimmune cellsalso are produced by fatcellscalled adipocytes. These interferons drive a constant low-level, chronicimmune responsethat amplifies "vigor" to a cycle of inflammation within white adipose tissue (WAT). More common...
In both situations, a key enzyme that moves copper in and out of cells is mutated, causing misregulation and copper overload in the liver. The condition is also characterized by bloated fat cells. He and his team discovered that in the mice, copper is hoarded by the liver, basically starvi...
In recent years, scientists have discovered that there are also beige fat cells without the UCP1 protein, and that these also consume energy and thus produce heat. The research team from ETH Zurich and the participating institutions has now precisely characterized the new class of beige fat...
Computer illustration of white adipose cells Tiny fatty droplets in our cells are part of the immune system and help fight off bacterial infections. Until now the droplets were thought to be among the most vulnerable parts of the cell. Lipid droplets are
Brown fat cells contain mitochondria and are made of a larger number of oily droplets, which are also smaller than those that make up white fat. Brown fat seems to act similarly to muscle tissue in many ways and actually uses white fat for fuel at times. Within brown fat’s mitochondria ...
The brown fat cells express the ERR gamma gene all the time, not just in response to cold, and that white fat cells do not express the gene at all, researchers said. While 80 percent of normal mice are able to handle a temperature drop, all mice lacking ERR gamma did not tolerate the...
Unlike energy-storing white, or “bad,” fat cells, “good” brown fat cells make a protein called UCP1 that converts energy stored in glucose and fatty acids into heat to keep the body warm. When active, brown fat cells can also use energy stored by white fat cells, and as a result...