In this study, we determined that farnesyl diphosphate synthase (FDPS), a key enzyme in isoprenoid biosynthesis, plays an important role in maintaining glioblastoma stemness. A comparison of the mRNA expression in patient-derived glioblastoma sphere cells, which maintain stemness, and their ...
In this study, we determined that farnesyl diphosphate synthase (FDPS), a key enzyme in isoprenoid biosynthesis, plays an important role in maintaining glioblastoma stemness. A comparison of the mRNA expression in patient-derived glioblastoma sphere cells, which maintain stemness, and their ...
英文名称:Farnesyl Diphosphate Synthase (FDPS) Antibody (HRP),中文名称:法尼基二磷酸合酶(FDPS)抗体(HRP),产品货号:Catalogue No: abx316869,【FDPS抗体(HRP)是一种兔抗与HRP结合的FDPS多克隆抗体。目标法尼基二磷酸合酶(FDPS)反应性人
Objective: Farnesyl diphosphate synthase (FPPs) produces FPP which is considered a branch-point intermediate in the synthesis of sterols and isoprenylated ... Maria,Notarnicola,Caterina,... - 《Oncology》 被引量: 59发表: 2005年 Molecular interactions of nitrogen-containing bisphosphonates within fa...
中文名称:FDPS (Farnesyl Pyrophosphate Synthase, FPP Synthase, FPS, Farnesyl Diphosphate Synthase, FPS, KIAA1293) (AP) 中文同义词: 英文名称:FDPS (Farnesyl Pyrophosphate Synthase, FPP Synthase, FPS, Farnesyl Diphosphate Synthase, FPS, KIAA1293) (AP) 英文同义词: FDPS (Farnesyl Pyrophosphate Syntha...
Aminobisphosphonates (NBPs) are the first-choice medication for osteoporosis (OP); NBP treatment aims at increasing bone mineral density (BMD) by inhibiting the activity of farnesyl diphosphate synthase (FDPS) enzyme in osteoclasts. Despite its efficacy, inadequate response to the drug ...
In vitro studies identified non-bisphosphonate FPPS inhibitors that may help treat soft-tissue cancers. Further details on the research, next steps and licensing status are discussed in the article.SciBX: Science-Business eXchangedoi:10.1038/scibx.2010.1035None...
Some polymorphic genes have been previously shown to affect the efficiency of performed anti-osteoporotic therapy.Objective: to study the impact of farnesyl diphosphate synthase (FDRS) and geranylgeranyl diphosphate synthase (GGSPI) gene polymorphisms on BMD changes during 12-month therapy with ...
The prenyl diphosphate synthases, farnesyl diphosphate synthase (FDPS), and geranylgeranyl diphosphate synthase (GGDPS) are responsible for the production of two key isoprenoids farnesyl diphosphate (FPP) and geranylgeranyl disphosphate (GGPP). Not only do these isoprenoid diphosphates serve as ...
Therefore, the present study evaluated the effects of risedronate (a bisphosphonate) on taste bud cells. Expression analyses revealed that farnesyl diphosphate synthase (FDPS, a key enzyme in the mevalonate pathway) was present in a subset of mouse taste bud and tongue epithelial cells, especially...