SCHWENDER S, GROSMANN R, KELLER F: High prevalence of factor V Leiden mutation is detected in a north to south axis through Germany. Lab Med 21: 347-353, 1997.S. Schwender, R. Großmann, F. Keller. (1997) High Prevalence of Factor V Leiden Mutation is Detected in a North ...
By looking for the FV:Q506 mutation with a PCR-based DNA test we found a prevalence of the mutation in heterozygote individuals of 6.92% and for homozygote individuals of 0.19% in the study group. At a cutoff ratio of 2.2 the chromogenic assay on the BCT shows a specificity of 89.9% (...