The meaning of FACTOR V LEIDEN is a point mutation producing an abnormal version of factor V that is resistant to inactivation and causes prolonged clotting of blood.
(redirected fromFactor V Leiden mutation) Thesaurus Medical Legal Acronyms Encyclopedia mu·ta·tion (myo͞o-tā′shən) n. 1.The act or process of being altered or changed. 2.An alteration or change, as in nature, form, or quality. ...
In a wild type individual, the factor V protein activates prothrombin to form thrombin, which is involed in the clotting pathway. Factor V Leiden is a variant of the factor V protein, with a G> A substitution at nucleotide position 1,691 in the F5 gene. The substitution leads to aV ...
Factor V Leiden mutation is a rare anomaly, which is prone to increase the thrombotic incidents in those who have the abnormality compared to the normal population. Herein, we report a patient with Factor V Leiden mutation, which was detected post-operatively during evaluation of ecchymosis and ...
Synonyms for Factor V Leiden mutation in Free Thesaurus. Antonyms for Factor V Leiden mutation. 34 synonyms for mutation: anomaly, variation, deviant, freak of nature, change, variation, evolution, transformation, modification, alteration, deviation...
factor-V Leidenfactor-V Leiden A common mutation of coagulation factor-V gene, which is found in 3 to 8% of Caucasians, and results in resistance to activated C protein and an increased risk in deep-vein and other thromboses. Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights...
Factor V Leiden 第五凝血因子；莱登第五因子 第五凝血因子 检验第五凝血因子(Factor V leiden)上的G1691A突变：造成容易产生血栓的体质(血栓病, thrombophilia)。北美洲有 5% 的人遗传有莱登第五因子 ( Factor V Leiden )﹐影响凝血功能。 年长﹑肥胖﹑抽烟﹐与及曾经出现过静脉栓塞症状的人士﹐再次...
Factor V Leiden Mutation 来自 Semantic Scholar 喜欢 0 阅读量: 31 作者: JD Johnson 摘要: The factor V Leiden mutation is the most common congenital prothrombotic disorder described. Although patients may have a 79 -fold increased risk of thrombosis, lifelong anticoagulation should be reserved ...
Factor V Leiden mutation is reportedly the most common hereditary risk factor for thrombosis. Spontaneous venous thromboses in children with factor V Leide... KJ Broxterman,P Mathew,L Chicoine - 《Journal of Pediatric Hematology Oncology》 被引量: 44发表: 2000年 Arterial embolism to the upper ex...
Clinical Significance:This test detects the factor V Leiden variant, the most common cause of inherited thrombophilia; it may be used to evaluate individuals with a strong personal or family history of venous thromboembolism (VTE) and inform treatment or preventive decisions [1]. ...