Drug absorption depends on the lipid solubility of the drug, its formulation and the route of administration. A drug needs to be lipid soluble to penetrate membranes unless there is an active transport system or it is so small that it can pass through the aqueous channels in the membrane. ...
多股软铜引线与扁铜引线焊接时，应先将多股软引线端头用细铜线绑扎并打扁，在导线上搭接的长度应为导线宽度的（）倍
Passage A: Pharmaceutical Factors Affecting Drug Bioavailability In order to design a drug product that will deliver the active drug in the most bioavailable form, the pharmacist must consider (1) the type of drug product (e.g. solution, suspension, suppository); (2) the nature of the exc...
The two most important physicochemical factors that affect both the extent and the rate of absorption are lipophilicity and solubility. The rate and extent of absorption are governed by the solubility, permeability and stability of the drug, with solubility being a pH-dependent parameter for weak ...
解析 答案:Factors that can influence the absorption of a drug include the route of administration, the formulation of the drug, the presence of food in the stomach, the pH of the gastrointestinal tract, and the individual's health status....
解析 答案:The main factors that influence drug absorption include the chemical properties of the drug, the route of administration, the presence of food in the gastrointestinal tract, the pH of the environment, and the permeability of biological barriers....
The issues discussed in the conference involved physiological factors affecting drug absorption, the role of pre-systemic effects on bioavailability (BA), the impact of variability in bioequivalence (BE) studies, and a final closing panel session on unresolved issues in BA/BE regulations. Several ...
Accounting for reasonableness: exploring the personal internal framework affecting decisions about cancer drug funding. Health Policy. 2008;86:381–90. Article PubMed Google Scholar Thew S, Sutcliffe A, Procter R, de Bruijn O, McNaught J, Venters CC, et al. Requirements engineering for E-...
In terms of its own factors, bone mineral density is generally considered to be an important factor affecting the settlement of the fuse, and the relationship between bone mineral density and end plate strength has become more and more clear. Hou et al. (17) found through biomechanical tests ...
In addition to gene variants, epigenetics can influence the expression of genes, thereby affecting cell differentiation, development, and disease risk. In recent years, several studies have suggested that circulating free DNA (cfDNA) methylation can serve as a predictive biomarker for tissue injury, ...