Factor VIII is a critical blood clotting factor, which forms a complex with the serine protease factor IXa upon activation to convert factor X to factor Xa, which in turn activates thrombin. Deficiency or dysfunction of the protein leads to hemophilia A, a common X-linked disorder. Structures ...
因子VIII的编码基因上有一些位点可以结合铁合蛋白,所以铁的水平可以调控因子VIII的基因,这也许是二者之间关联的机理。 china.labmedica.com china.labmedica.com [...] receiving transfusions of blood clottingfactor VIII,andall four died of AIDS.46 In the 1990s, because China had banned imports of blood...
reactions that allow the body to form a clot to prevent the further loss of blood. Factors VIII and IX are located in the intrinsic arm of the coagulation cascade. Theabsence, or a decrease in the level, of either of these factors will arrest the clotting process, leading to prolonged...
blood clotting factor Coagulation factor, see there. McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc. Want to thank TFD for its existence?Tell a friend about us, add a link to this page, or visitthe webmaster's page for free fun content. ...
Factor VIII Factor VIIIis a medication used to treat and prevent bleeding in people with hemophilia A and other causes of low factor VIII. Earlier, blood clotting factor VIIIs used to be produced from human plasma. In 1992, the U.S. Food and Drug Administration (FDA) approved recombinant ...
clotting 凝固 blood n. 1.[U]血 2.-blooded(构成形容词)有...类型的血的 3.[C]纨绔子弟;花花公子 4.[U]血统;家世 v.[T]让(初试) factor n.[C] 1.因素 2.【数】因数,因子 3.(企业的)代理人,代理商 4. 【苏格兰】地产经管人,管家 X Factor X音素 X Factor 是一个发源自英国的电视选...
The resulting disease is a severe form of a blood clotting defect (Hemophilia A) where no Factor VIII activity is detectable. This inversion is caused by an intrachromosomal recombination event of two homologous regions found on the X-chromosome. One repeat is located in intron 1 (int1h-1) ...
美 英 un.凝血因子;血凝因子 英汉 un. 1. 凝血因子 2. 血凝因子
The yield of factor VIII clotting activity (VIII:C) and factor VIII antigen (VIIIR:Ag) was compared in blood drawn from the treated and untreated donors. To prevent degradation of VIII:C by fibrinolysis, tranexamic acid was added to the plasma from treated donors immediately after separation ...
The present invention relates to method for the production of recombinant muteins blood clotting factor VIII, utilizing an immortalized human cell line stably expressing viral transcription activator proteins and carrying a vector having a promoter functionally linked to a DNA sequence coding for a blood...