in which the prime elements π1,···, πm are pairwise-nonassociate and ε is a unit of the ring D. In case factorization is unique, the prime elements π1,···πm are determined up to associates and the exponents k1,… km are uniquely determined. The classical example of a rin...
An important quantity for a detection medium is the w- value, which is defined as the average energy required to create an electron-ion or electron-hole pair in gases or semiconductors, respectively. In a given ionization medium the w-value is nearly identical for beta or gamma radiation ...
The first five years of X-Factor saw the introduction and initial development of Apocalypse, the transformation of Angel to Archangel, and the genesis of Cable. It also served as a sort of home-base for many line-wide storylines such as Fall of the Mutants and Inferno – both played out ...
Any clones found to have expansion or shrinkage of either the polyQ or polyG site in the AR were corrected by replacing the 1510-base-pair (bp) KpnI-KpnI fragment with that of the WT AR sequence from peGFP-C1-AR. For peGFPC1A-V7, the V7 variant of AR was generated from peGFP-C1-...
The gene regulatory code and grammar remain largely unknown, precluding our ability to link phenotype to genotype in regulatory sequences. Here, using a massively parallel reporter assay (MPRA) of 209,440 sequences, we examine all possible pair and tripl
An improved power factor DC power supply in accordance with the present invention (100 or 200) employs a power factor correcting network (120), a full-wave rectifier means (122), a pair of filter capacitors (124 and 126), and three current steering diodes (128, 130 and 132). The power...
FOXO proteins recognize two 8 base pair sequences distinct from a core forkhead consensus sequence: the insulin response element present in the IGFBP1 promoter [TT(A/G)TTTTG] and the DAF-16 family binding element [TT(G/A)TTTAC] (Furuyama et al., 2000; Tang et al., 1999). FOXOs ...
The structural superposition of all six copies, three from the p18mAUG1 structure and three from the p18mAUG2 structure (Fig. 2b), have an RMSD of <0.25 Å for all pairwise alignments overall Cα atom positions. There is no additional density for residues 249 to 259 that constitute the...
picking pools of 200 to 500 colonies each and isolating plasmid DNA from each pool; transfecting the plasmid DNA into suitable host cells for expressing CSF protein; culturing the transfected cells and assaying the supernatant for CSF activity; and selecting CSF positive pools and screening the col...
of 200 nM secondary antibody. Regeneration was performed at the end of each binding experiment by a 2-min pulse of 10 mM glycine, pH 2.0. The entire process was repeated for all pairwise permutations of the antibodies listed in Table 1 except for 4F136 which could not be used as ...