factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and ...
In response to signals that induce NF-kappaB, such as cytokines and growth factors, the encoded protein undergoes phosphorylation, triggering its rapid ubiquitination and proteasomal degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] Amplicon ...
Chakraborty [12] reported a thermodynamic model for understanding the surface – energy and the surface – structural interaction factors of different non polar gases onto activated carbons. Wang et al. [13] studied activated carbon methanol pair, the adsorption properties of activated carbon (AC)/...
Specifically, BFReg-NN used the existing knowledge (e.g., protein-protein interaction network) to build a “white-box” architecture of biological factors, and learn the factor functions in cells by graph neural networks, ultimately giving insight into the mechanisms of the whole system (Fig. ...
They found that there are many factors that influence the texture development in addition to just the anisotropy of the grain boundary properties. One important aspect was that the initial, as-deformed microstructure had highly elongated grain shapes; these were instantiated using a tool called a ...
Specifically, BFReg-NN used the existing knowledge (e.g., protein-protein interaction network) to build a “white-box” architecture of biological factors, and learn the factor functions in cells by graph neural networks, ultimately giving insight into the mechanisms of the whole system (Fig. ...
Position-dependent function of human sequence-specific transcription factors Article Open access 17 July 2024 Global reference mapping of human transcription factor footprints Article Open access 29 July 2020 Introduction The vast majority of the human genome is noncoding. Nonetheless, even as the ...
Multiple stage-specific transcription factors, cell cycle factors and signaling regulatory proteins are involved in monocyte/macrophage (MO/MΦ) differentiation [9]. Dysregulation of MO/MΦ differentiation can lead to various diseases, such as inflammation, autoimmune disease and cancer. In recent ...
The PoDL circuit affects the communication channels, with return loss and signal decay (or droop) being two significant factors.Return loss is a measure of signal reflections likely to occur on a network and is caused by impedance mismatches at all locations along a cable link. Return loss is...
Selection of an appropriate antigen and antibody is therefore one of the key factors in developing an accurate and sensitive immunoassay for an analyte or disease marker. The efficacy of an immunoassay depends upon specific recognition of the antigen by antibody and the affinity of an antibody for...