Jun ZJ, Ping T, Lei Y, Li L, Ming SY, Jing W (2006) Prevalence of factor V Leiden and prothrombin G20210A mutations in Chinese patients with deep venous thrombosis and pulmonary embolism. Clin Lab Haematol 28:111-116. doi:10.1111/j.1365- 2257.2006.00757.x...
产品编号 中文名称 英文名称 SRNC-14/316 Factor IX activated (FIXa) 2nd WHO International Standard Factor IX activated (FIXa) 2nd WHO International Standard SRNC-04/224 Factor V Leiden, Human gDNA, 1st
In addition to the genetic variants currently used in clinical assessment of hereditary thrombophilia (e.g., Factor V Leiden, prothrombin mutation) there are other more recently discovered common gene variants that contribute to VTE risk15,16,17. However, even when these are also incorporated into...
Factor H-related protein 1 (FHR-1) is a member of the human complement factor H protein family (its mouse homologue is named FHRE), which consists of complement factor H, a splice variant of factor H (factor H-like-1 (FHL-1)), and five FHR proteins (FHR-1 through FHR-5)8,9. ...
Bassuk AG, Anandappa RT, Leiden JM: Physical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cells. J Virol. 1997, 71: 3563-3573. PubMed PubMed Central Google Scholar Graves BJ, ...
(chr1:169519049TG > A) known as factor V Leiden, (F5for gene, FV for protein) and a custom design was used for targeting rs1799963 (chr11:46761055G > A) in coagulation factor 2/prothrombin),F2(F: 5’- GTGTTTCTAAAACTATGGTTCCCAATAAAAGT-3’, R: 5’- CCATGAATAGCACTGGGAGC...
. Several initiatives have been instigated discussing the potentially harmful effects of such practices and providing recommendations for sensible and responsible use of metrics such as the JIF—most prominently the ‘San Francisco Declaration on Research Assessment’ (DORA),Footnote 1 the ‘Leiden ...
Prevalence of factor V Leiden and prothrombin G20210A mutations in Chinese patients with deep venous thrombosis and pulmonary embolism. Clin Lab Haematol. 2006; 28 :111–6. [ PubMed ]Jun ZJ,Ping T,Lei Y,et al.Prevalence of factor V Leiden and prothrombin G20210A mutations in Chinese ...
The most profoundly regulated gene, Tissue Factor Pathway Inhibitor 2 (TFPI2), was fivefold increased following MEG8 silencing. TFPI2 has previously been described as an inhibitor of angiogenesis. Mechanistically, MEG8 silencing resulted in a reduction of the inhibitory histone modification H3K27me3...
The genes were divided into five groups on the basis of gene ontology Full size image By cross-referencing the transcriptome and the ChIP-seq data sets, we could identify 95 putative direct target genes of GABPα, among which 70 and 25 were activated or repressed by GABPα, respectively (...