Genetic Testing for Factor V LeidenCPT(R)* Codes83891 Molecular diagnostics; isolation or extraction of highly purified nucleic acid, each nucleic acid type (DNA or RNA)83892 Molecular diagnostics; enzymatic digestion, each enzyme treatment83896 Molecular diagnostics; nucleic acid probe, each83898 ...
b.The process by which such a change occurs, either through an alteration in the nucleotide sequence coding for a gene or through a change in the physical arrangement of the genetic material. c.The nucleotide sequence, trait, or individual that results from such a change. ...
PATHOGENIC MECHANISMS AND MOLECULAR BASIS Factor V Leiden is a genetic disorder characterized by a poor anticoagulant response to APC. APC is a natural anticoagulant protein that cleaves and inactivates procoagulant Factors Va and VIIIa, thereby downregulating further thrombin generation.5,6 APC in...
Analytic validity of genetic tests to identify factor V leiden and prothrombin G20210A. Am J Hematol, in press.Emadi A, Crim MT, Brotman DJ, Necochea AJ, Samal L, Wilson LM, et al. Analytic validity of genetic tests to identify factor V Leiden and prothrombin G20210A. Am J Hematol. ...
Medical genetic test reporting for cystic fibrosis (deltaF508) and factor V Leiden in North American laboratories. Genet Med 2002;4:324 -327.Andersson HC, Krousel-Wood MA, Jackson KE, Rice J, Lubin IM: Medical genetic test reporting for cystic fibrosis (deltaF508) and factor V Leiden in...
Factor V Leiden, Antithrombin III, Protein C, Protein S, and Protein Z Deficiencies; Prothrombin G20210A Polymorphism; and von Willebrand Factor Hereditary Deficiencies Genetic modifications that affect function or concentration of the regulatory coagulation proteins in the hemostatic pathways are associated...
1) Factor V Leiden mutation FV Leiden突变 1. OBJECTIVE: TheFactor V Leiden mutation(FVL mutation) represents the most common genetic risk factor for venous thromboembolism. 目的FV Leiden突变是导致静脉血栓栓塞(VTE)的最常见的遗传因素,然而该突变与缺血性脑血管病(ICVD)的关系尚不明确,而且其分布存在种...
Testing with allele-specific polymerase chain reaction for FII mutation and factor V Leiden showed a double homozygous pattern for both factor V Leiden and c.*97G > A FII mutation (Fig. 2). Since this genetic combination is unusual, next-generation DNA sequencing of the factor V and factor...
Factor V Leiden mutation is a common genetic risk factor for venous thrombosis. It has been documented in up to 65% of patients with unexplained venous thr... Annette,M,Miles,... - 《Primary Care Update for Ob/gyns》 被引量: 6发表: 1999年 The Factor V Leiden mutation is associated ...
5. Bertina RM, Koelemen BP, Koster T, et al. Mutation in blood coagulation factor Ⅴ associated with resistance to activated protein C [J]. Nature, 1994, 369(6475): 64-67. 6. Rees DC, Cox M, Clegg JB, et al. World distribution of factor Ⅴ Leiden [J]. Lancet, 1995, 346(8983...