Nanomedicine 15, 1001–1018 (2020). Article CAS PubMed Google Scholar Salamon, P., Mekori, Y. A. & Shefler, I. Lung cancer-derived extracellular vesicles: a possible mediator of mast cell activation in the tumo
Extracellular vesicles (EVs) are membrane structures that cells use for storage, transport, communication, and signaling. Recent research has focused on EVs as natural nanoparticles for drug delivery. This review sheds light on the application of EVs in cancer therapy, such as targeted chemotherapy,...
Cancer-derived extracellular vesicles (EVs) are regarded as having promising potential to be used as therapeutics and disease biomarkers. Mechanistically, EVs have been shown to function in most, if not all, steps of cancer progression. Cancer EVs, including small EVs (sEVs), contain unique biomo...
2. Extracellular vesicles 3. Bacterial EVs in cancer immunotherapy 4. Development and clinical translation of BEVs 5. Conclusion CRediT authorship contribution statement Declaration of competing interest ReferencesShow full outline Cited by (37) Figures (4) Tables (4) Table 1 Table 2 Table 3 Tabl...
Extracellular vesicles (EVs) are emerging as critical mediators of intercellular communication in the tumor microenvironment (TME), profoundly influencing cancer progression. These nano-sized vesicles, released by both tumor and stromal cells, carry a diverse cargo of proteins, nucleic acids, and lipids...
Recent progress in the CRISPR-Cas9 systems has led to breakthroughs in gene editing tools because of its high orthogonality, versatility, and efficiency. However, its safe and effective administration to target organs in patients is a major hurdle. Extracellular vesicles (EVs) are endogenous ...
Extracellular vesicles (EVs) play a crucial role in the complex process of cancer metastasis by facilitating cellular communication and influencing the microenvironment to promote the spread and establishment of cancer cells in distant locations. This paper explores the process of EV biogenesis, explaining...
Extracellular vesicles (EVs) play important roles in intercellular communication. They are stable, biocompatible and can easily enter histocytes, which makes them particularly useful in cancer therapy. However, natural EVs have limitations in targeting and killing cancer cells. Numerous studies have show...
Chemoresistance and metastasis are the major challenges for the current ovarian cancer treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is critically important for developing novel therapies. The advances in extracellular vesicles (EVs) research in recent years have attracte...
Extracellular vesicles in cancer: exosomes, microvesicles and the emerging role of large oncosomes. Semin. Cell Dev. Biol. 40, 41–51 (2015). CAS PubMed PubMed Central Google Scholar Ostrowski, M. et al. Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat. ...