Extracellular vesicles (EVs) are a group of secretory vesicles with cell-derived membrane and contents. Due to the cargo delivery capability, EVs can be designed as drug delivery platforms for cancer therapy. Biocompatibility and immune compatibility endow EVs with unique advantages compared with other...
Extracellular vesicles (EVs) are a group of secretory vesicles with cell-derived membrane and contents. Due to the cargo delivery capability, EVs can be designed as drug delivery platforms for cancer therapy. Biocompatibility and immune compatibility endow EVs with unique advantages compared with other...
Extracellular vesicles (EVs) are nanoscale vesicles derived from cells that mediate intercellular communication by transporting bioactive molecules. They play significant roles in various physiological and pathological conditions. EVs hold great potential as novel biomarkers of diseases, therapeutic agents, and...
6.Extracellular vesicles in cancer therapy. 癌症治疗中的细胞外囊泡。 [Semin Cancer Biol] PMID: 35688334 摘要:细胞外囊泡 (EVs),包括各种携带细胞衍生货物的膜包裹纳米颗粒,在生理和病理过程中介导一种主要类型的细胞间通讯。癌细胞和非癌细胞都...
Pancreatic cancer (PC) is one of the leading causes of cancer-related death worldwide due to delayed diagnosis and limited treatments. More than 90% of all pancreatic cancers are pancreatic ductal adenocarcinoma (PDAC). Extensive communication between tu
Extracellular vesicles (EVs) play important roles in intercellular communication. They are stable, biocompatible and can easily enter histocytes, which makes them particularly useful in cancer therapy. However, natural EVs have limitations in targeting and killing cancer cells. Numerous studies have show...
Impact of cancer cell-derived extracellular vesicles on recipient cells. This figure illustrates the role of EVs released by cancer cells in interacting with various recipient cells, affecting their functions and behaviors: (A)Intercellular Communication: EVs from cancer cells can travel to adjacent or...
< 200 nm in diameter)—it is important to distinguish between the terms “sEV” and “exosome”; the small EV population comprises both small exosomes and exosomes. Among the extensively studied and commonly used in tumor therapy are sEV [4]. sEV, also known as intraluminal vesicles, form...
Extracellular vesicles: emerging targets for cancer therapy Wood, Extracellular vesicles: emerging targets for cancer therapy, Trends Mol. Med. 20 (2014) 385-393.Vader P, Breakefield XO, Wood MJ. Extracellular ... P Vader,XO Breakefield,MJA Wood - 《Trends in Molecular Medicine》 被引量: 20...
Extracellular vesicles (EVs) play a pivotal role in intercellular communication and have been implicated in cancer progression. Hypoxia, a pervasive hallmark of cancer, is known to regulate EV biogenesis and function. Hypoxic EVs contain a specific set of proteins, nucleic acids, lipids, and metabol...