Extracellular matrixOsteoblastsInsulin-like growth factor binding protein-2 (IGFBP-2) in its native form had little affinity for extracellular matrix (ECM) derived from human or rat osteoblastic cells. However, in the presence of IGFs, IGFBP-2 binding to ECM was markedly enhanced, with IGF-II ...
Extracellularmatrix proteinsappear to be made up of building blocks (‘structural motifs’), which areprotein domainswith extensive homology to existing protein structures. For instance, threefibronectindomains are reproduced in many other proteins; the epidermal growth factor-like domain also appears in...
Epidermal growth factor-containing fibulin-like extracellular matrix protein 1, EFEMP1, a novel tumor-suppressor gene detected in hepatocellular carcinoma ... Background Although hepatocellular carcinoma (HCC) is one of the commonest cancers worldwide, the underlying molecular mechanisms contributing to ...
An extracellular matrix protein that supports the adhesion and migration of inflammatory cells. It has recently been recognized as an immunoregulatory TH1-type cytokine. Toll-like receptor family (TLR family). A family of receptors that are unique to microorganisms that recognize conserved products (su...
2. Itwastheimportantpathologicbasisofdiabeticnephropathythatextracellularmatrixgraduallyaccumulation. 细胞外基质进行性积聚是导致糖尿病肾病发生、发展的重要病理基础。 dictsearch.appspot.com 3. Thehistologicfindingswereofahyalinecartilage-likemassconsisting ofmaturechondrocytesandanextracellularmatrix. ...
G. et al. Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. J. Extracell. Vesicles 1, https://doi.org/10.3402/jev.v1i0.18396 (2012). Park, J. E. et al. Hypoxia-induced tumor exosomes promote M2-like macrophage polarization of ...
The biology function effect of extracellular matrix protein 1on breast tumor cell MCF-7 line and HUVEC Objective To investigate the biological effect of extracellular matrix protein 1(ECM1) on breast tumor cell MCF-7 line and HUVEC.Methods ECM1-pEGFP-N2 was ... Y Hou,R Zhong,J Lou,......
Urethral stricture secondary to urethral injury, afflicting both patients and urologists, is initiated by excessive deposition of extracellular matrix in the submucosal and periurethral tissues. Although various anti-fibrotic drugs have been applied to u
Cell Junctions, Cell Adhesion, and the Extracellular Matrix:细胞连接,细胞粘附,细胞外基质 热度: nature22978-The extracellular matrix protein agrin promotes heart regeneration in mice 热度: Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in ...
and used the powder as the matrix of a gel exclusion column. Then proteins of various sizes were added to the top of the column. If a protein was too large to enter the “pore space,” it eluted in the voidvolume—that is, it was not retarded by the column. Proteins that were reta...