Our laboratory has previously reported that the tumour promoting effect of MT4-MMP is similarly observed when tumour cells are injected subcutaneously or in the mammary fat pad (Paye et al, 2014). Tumour growth was assessed by measuring the length and width of tumours every 3–4 days. Tumour...
We show here that the addition of calcium (Ca) has no positive effect on the nodulation kinetics shown by LPU83 at low pH, but does retrieve the competition capacity of S. meliloti strains in acidic media, likely by improving the ability of these bacteria to attach to plant roots. In ...
PRMT4 promotes ferroptosis to aggravate doxorubicin-induced cardiomyopathy via inhibition of the Nrf2/GPX4 pathway. Cell Death Differ. 2022;29:1982–95. https://doi.org/10.1038/s41418-022-00990-5. Article PubMed PubMed Central CAS Google Scholar Wang Y, Zheng L, Shang W, Yang Z, Li T,...
Nonetheless, high lignin content has a negative effect on jute fiber separa- tion as well as fiber fineness [2, 8]. In fact, the lignin con- tent of jute fibers is comparatively high (~ 15%), which distinguishes them with other non-wood bast fibers such as ramie, hemp and flax ...
Lane 1 indicates unfractionated normal BM cells; lanes 2-9, various myeloid cell lines known as Mo7E, AML5, KG1, TF1, U937, HL60, K562, THP1; lanes 10-17, various lymphoid cell lines known as Im9, Daudi, Raji, Jurkat, CC119, MT4, Hut102, and Hut78. AHI-1 expression is ...
HTLV-1-transformed T-cell lines (HUT102, MT2 and MT4) expressed high levels of Tax. The graph shows relative band intensity of p-PTEN (Ser380/ Thr382/Thr383) and non-p-PTEN (Ser380/Thr382/Thr383). Each p-PTEN or non-p-PTEN value was divided by the total PTEN value for a ...
Furthermore, knockdown of NRF-1 using a siRNA had no effect on the activity of this construct indicating that NRF-1 no longer binds and activates the GABPβ promoter. Mutation of nucleotides 4 and 5 did not decrease GABPβ promoter activity (Figure 9d, mT4, mT5) despite the diminished ...
compared with subjects with no history of psychiatric illness (controls), changes in gene expression in the dorsolateral prefrontal cortex from two subgroups of subjects with schizophrenia, one with a marked deficit in muscarinic M1 receptors (muscarinic receptor-deficit schizophrenia (MRDS)), would ide...
Co-activator-associated arginine methyltransferase 1 (CARM1) also known as PRMT4 methylates specifically the dimeric form of PKM2 at Arg445, Arg447, Arg455 residues in the C domain which is PKM2 exon 10 located. TEPP-46 and FBP, the allosteric activators that induce PKM2 tetramerization limits...
Cells split 1:5 were transiently transfected the next day by using 30 μg of a mixture (10:1 wt/wt) of two plasmids (pMT4 and pRSVTag, respectively) by the Ca2PO4 precipitation procedure (26). Plasmid pRSVTag (29) carries a gene encoding SV40 large tumor (T) antigen that promotes ...