During the ageing process, there is a progressive decline in serum total and free testosterone levels, increase in sex hormone binding globulin (SHBG), and moderate increase in luteinizing hormone (LH). Incidence of hypogonadism (total testosterone < 3 ng/ml) accounts 15–20% in men betwee...
At the level of whole neurons, intrinsic excitability influences the input-output function, in terms of firing rate for a given strength of input. Dynamic range adaptation provides a finer control over this function to constrain firing rates over time to within a desired physiological range. ...
the association betweenACE1D/I polymorphism and comorbidities. The best explanation for this discrepancy could be that the D allele and DD subtypes are associated with comorbidities, but the DD genotype alone does not have an exceptionally large effect. This is also expected since theACE1D/I ...