Analysis tools are available for specific tasks relevant to proteomics, similarity searches, pattern and profile searches, post-translational modification prediction, topology prediction, primary, secondary and tertiary structure analysis and sequence alignment. These databases and tools are tightly interlinked...
(e.g. metallothionein), this calculation may have 10% or more error. ProtParam predicts an estimatedhalf-lifebased on the “N-end rule,” which relates the in vivo half-life of a protein to the identity of its N-terminal residues.9Note that ProtParam does not consider post-translational ...
9、result from unspecific cleavage of proteins from their experimental masses, taking into account artefactual chemical modifications, post-translational modifications (PTM) and protease autolytic cleavage 鑑定一由實驗質譜結果所得的蛋白質胜肽,並考慮到人工的化學修飾、轉譯修飾(PTM)及蛋白質自體溶解等因素。1...
To utilize the extensive annotation available in the Swiss-Prot database (1) wherever possible, in particular the position-specific annotation in the Swiss-Prot feature tables to take into account posttranslational modifications and protein processing. 2. To develop tools specifically, but not exclus...
ExPASy使用初探
These include Compute pI/Mw, a tool for predicting protein isoelectric point (pI) and molecular weight (Mw) in a 2-D gel; PeptideMass, a tool for theoretically cleaving proteins and calculating the masses of their peptides and any known cellular or artifactual posttranslational modifications; ...
MAIN FEATURES Access to a large set of bioinformatics resources The previous ExPASy server was mainly dedicated to bioinformatics related to proteomics (protein identifica- tion, post-translational modifications, etc.), and only Figure 1. ExPASy homepage. Nucleic Acids Research, 2012, Vol. 40, Web...
computations and predictions, they use the annotations relevant SWISS-MODEL (14,15) is an automated knowledge-based to post-translational modifications and processing, as well as protein modelling server. It is able to build models for the splice variants documented in the SWISS-PROT feature ...
Protein characterization tools in the context of PMF experiments include FindMod, to predict posttranslational modifications and single-amino acid substitutions; GlycoMod, a tool to predict the possible compositions for glycan structures, or compositions of glycans attached to glycoproteins; FindPept, to ...
(PMF) tool. Protein characterization tools in the context of PMF experiments include FindMod, to predict posttranslational modifications and single-amino acid substitutions; GlycoMod, a tool to predict the possible compositions for glycan structures, or compo- ...