This review summarizes the recent advances on exosome therapy with animal models of ED, and proposes the prospect of future research in order to provide a basis for clinical trials and clinical translation.Huan FengWei PengZhiyao DengJihong Liu...
was significantly upregulated in patients with OLP, and that exosome miR-34a-5p was positively correlation [81]. It is common for exosomes to play a diagnostic role in OLP, and there is still a lack of studies related to exosome therapy for OLP. Hard and soft tissue trauma defects of the...
In recent years, therapies utilizingextracellular vesicleshave garnered significant attention among the industry stakeholders for the treatment of diverse target indication, primarily owing to the various benefits offered by them, including target specificity, enhanced tissue regeneration, and reduced inflammati...
Advances and challenges of mRNA therapy Transformative advances in mRNA therapies development Over the past decade, therapeutic mRNAs have brought about a revolution in the field of drug development. Modified nucleotides in mRNA sequences can code for a wide range of proteins and thus treat various ...
Nevertheless, the specific mechanisms by which exosome signals regulate TAMs in gliomas still need to be defined. Understanding the intricate interaction between gliomas and TAMs could open a new vista for the therapy. The utilization of exosomes as clinical biomarkers still demands further evaluation ...
Epigenetic therapy targeting bone marrow mesenchymal stem cells for age-related bone diseases. Stem Cell Res Ther. 2022;13(1):201. Article PubMed PubMed Central Google Scholar Tan SHS, Wong JRY, Sim SJY, et al. Mesenchymal stem cell exosomes in bone regenerative strategies-a systematic ...
In this review, we discussed the need for exosomes in skin therapy together with the current challenges. Moreover, the functional roles of exosomes in terms of skin treatment and regeneration are overviewed. Finally, we highlighted the major limitations and the future perspective in exosome ...
Responsive Exosome Nano-bioconjugates for Synergistic Cancer Therapy Angewandte Chemie (International ed. in English), 59 (5) (2020), pp. 2018-2022 CrossrefView in ScopusGoogle Scholar [84] M. Fan, H. Liu, H. Yan, et al. A CAR T-inspiring platform based on antibody-engineered exosomes...
IL-2 [42], which can then be used for the development of therapeutic vaccines for tumor immunotherapy. In addition, when used as a drug carrier, DEX has been shown to stimulate cytotoxic T cells in cancer therapy and inhibit tumor growth in animal models. Lu et al. [43] treated a ...
Along with that, it is intriguing to find out whether this combinatorial therapy could be an effective measure for treating CSC mediated EMT in TNBC. Poor drug solubility, half-life, and drug resistance as a result of insufficient drug binding with the particular ligands of the tumors are the...