Excess brain fluid may cause bad vision in astronautsdoi:10.1016/S0262-4079(19)30805-XCrane, LeahNew scientist
Treatment with GH reverses some of these abnormalities but can cause fluid retention, diabetes mellitus, and high blood pressure (hypertension). Growth hormone excess Excess GH production is most often caused by a benign tumour (adenoma) of the somatotroph cells of the pituitary gland. In some ...
Approximately 60% of a typical adult’s body weight consists of fluid. Body fluid is located in two fluid compartments: the intracellular space (fluid in the cells) and the extracellular space (fluid outside the cells). Approximately two-thirds of body fluid is in the intracellular fluid (ICF...
Annexin A2 is one of the proteins found in the junctions between tightly packed endothelialcells, which lineblood vessels. The junctions function like gates keeping fluid out. When oxygen is low in the lung, compounds called phosphates can stick onto the gates, jamming them open and allowing flu...
In ALS, astrocytes are unable to efficiently reuptake glutamate in the synapses and, thus allow elevated glutamate levels in the brain's extracellular fluid (ECF) to develop glutamate-mediated excitotoxicity via activation of glutamate receptors and neuroinflammation (Rosenblum and Trotti, 2017). High ...
et al. Lipidomics reveals cerebrospinal-fluid signatures of ALS. Sci. Rep. 7, 17652 (2017). Article CAS PubMed PubMed Central Google Scholar Cutler, R. G., Pedersen, W. A., Camandola, S., Rothstein, J. D. & Mattson, M. P. Evidence that accumulation of ceramides and cholesterol ...
The dominant orthodox biological concept of schizophrenia is that it is somehow related to an excess of dopamine activity in critical areas of the brain. The outstanding pieces of evidence in favor of this concept are that all the commonly used anti-schizophrenic drugs are blockers of dopamine re...
uniquely increased in the brain fluid (CSF) of women with IIH. When the researchers, analysed human choroidal plexus tissue, which is the site in the brain where CSF is produced, they confirmed that androgens could increase the rate of CSF secretion, a potential driver for increased brain ...
(Fig.4d). Salt intake predicted epidermal water content, but not Na+or K+, independently of age, sex and BMI (Supplementary Fig.8); at variance with aging, the lack of any significant shift in the Na/K ratio in relation to salt intake would suggest a fluid accumulation evenly ...
The Fe-rich diet had no impact on Mn levels in the brain, bone, kidney, and blood in Slc39a14+/+ mice but did attenuate Mn excess in the brain, bone, kidney, and blood Mn excess in Slc39a14KO/KO mice except for the bone and kidney in female Slc39a14KO/KO mice (Fig. 6, B...