The case was referred to a laboratory immunologist to determine if the diagnosis of CVID was indeed accurate for this patient. Based on the clinical history of life-long recurrent infections, male gender, very low levels of immunoglobulins and nearly absent B cells, the differential diagnosis shoul...
Biotechnology, the use of biology to solve problems and make useful products. The most prominent area of biotechnology is the production of therapeutic proteins and other drugs through genetic engineering. Learn more about the development and application
During development, forced degradation studies highlighted some modifications in the structure of the molecule as confirmed by physicochemical assays. The cell-based assay to be developed should be able to detect a change in the dose response curve parameters and/or a shift in potency upon forced ...
Phosphate ions are found in water and can exist in different forms depending on how acidic or basic the water is. At a neutral pH, one type of phosphate ion is more common, while at lower or higher pH, different types of phosphate ions become more common. These different types of phospha...
Virulence assays, for instance, are used to determine the virulence of a pathogen in a laboratory setting. Factors, such as mortality rates,tissuedamage, or the presence of virulence genes, are quantified to gain insights into the virulence of certain strains and their potential to cause outbreaks...
Cell-Based Assays Radioimmunoassays Data Analysis in biotechnology, bioinformatics, and medical research Laboratory and Equipment 15 engineering technical skills to add to your PhD resume: Manufacturing: Forging, Welding, Assembling, etc. Quality Control Robotics Industrial /System Design and Analysis Concep...
The new Bayesian detector we introduce here calculates an approximation of the desired likelihood ratio and is based on diffuse but prior knowledge about the cell-cycle period time that has not been employed in earlier approaches. We compare the performance of the Bayesian detector introduced here ...
cells_assays_dict, cell_tfs, tf_cells, assay_cells_datatypes, header): """pairs matching chromosomes in motif_sites_input_dir and all_chromatin_makrs_all_cells_input_dir and calls overlay_resources_score_motifs Input: moitf instances input dir (one file per chr) chromatin data collectio...
Droplet-based microfluidics is a versatile tool to reveal the dose–response relationship of different effectors on the microbial proliferation. Traditional readout parameter is the temporal development of the cell density for different effector concentrations. To determine nonlinear or unconventional dose–...
cell-based permeability assayscentral nervous system (CNSpassive diffusion permeabilitypharmacodynamics (PDpharmacokinetics (PKSummary The effectiveness of a drug to modulate a disease state relies on the interplay between the pharmacokinetics (PK) and the pharmacodynamics (PD). Efficacy requires three ...