Novel investigational techniques based on magnetic resonance spectroscopy (MRS) have allowed real-time insight into the molecular defects in patients with type 2 diabetes, revealing that insulin resistance is a product of decreased insulin-stimulated skeletal muscle glycogen synthesis, which can mostly be...
Etiology of insulin resistance. Am J Med 119:S10-S16 Type 2 diabetes mellitus is a major cause of morbidity and mortality worldwide, and the prevalence is set to increase dramatically over the coming decades... KF Petersen,GI Shulman - 《American Journal of Medicine》 被引量: 1155发表: 20...
英文: Molecular etiology of insulin resistance中文: 胰岛素抵抗的分子遗传学病因 英文: Etiology and detection methods of gosling plague中文: 小鹅瘟病原学与检测方法的研究 英文: Etiology of aseptic meningitis prevalent in Xuzhou中文: 2001年徐州地区暴发性病毒性脑膜炎病原的研究 ...
However, in recent years, there has been a profound interest in the role that oxidative stress in the peripheral tissues plays to induce insulin resistance. The objective of this review is to focus on the mechanism of oxidative species generation and its direct correlation to insulin resistance, ...
Explores the role of very low-density lipoprotein triacylglycerol (VLDL-TAG) in the etiology of muscle insulin resistance. Ways for inducing insulin resistance in animals and humans; Direct effects of insulin on hepatic TAG secretion; Effect of prior metabolic state on the effects of insulin on he...
英文: Nosetiology and molecular biology analysis of rats infected with HFRS in Liaoning Province中文: 辽宁省鼠类感染肾综合征出血热的病原学及分子生物学检测比较 英文: The etiology is not known.中文: 其病名尚不明。英文: Molecular etiology of insulin resistance中文: 胰岛素抵抗的分子遗传学病因 ...
Insulin resistance, a common feature of PCOS that arises in part from adipose tissue dysfunction, results in compensatory hyperinsulinemia, which maintains normal glucose levels but adversely effects ovarian androgen production Abnormal folliculogenesis and gonadotropin production, particularly luteinizing hormone...
Objective To investigate tyrosine phosphorylation and protein expression of insulin receptor substrate-2(IRS-2)in adipose tissues of patients with polycystic ovary syndrome(PCOS),and explore molecular mechanisms of insulin resistance(IR) in PCOS. 目的研究多囊卵巢综合征患者脂肪组织胰岛素受体底物-2蛋白的...
The etiology of type 2 diabetes mellitus involves the induction of insulin resistance along with the disruption of pancreatic β-cell function and the loss of β-cell mass. In addition to a genetic predisposition, lifestyle factors seem to have an important role. Epidemiological studies indicate th...
These aspects, interacting or not with genetic factors, could explain the excess of body fat in large proportions worldwide. This article will focus on positive energy balance, high-fat diet, alteration in appetite control hormones, insulin resistance, amino acids metabolism, and the limitation of...