High- level production of ethylmalonyl-CoA pathway-derived dicarboxylic acids by Methylobacterium extorquens under cobalt-deficient conditions and by polyhydroxybutyrate negative strains. Appl Microbiol Biotechnol. 2015;99:3407-19.Sonntag, F., Mu篓 ller, J.E.N., Kiefer, P., Vorholt, J.A., ...
Synthesis of C5-dicarboxylic acids from C2-units involving crotonyl-CoA carboxylase/reductase: The ethylmalonyl-CoA pathway reductase (or its gene) can be used as a marker for the presence of the ethylmalonyl-CoA pathway, which functions not only in acetyl-CoA assimilation... TJ Erb,IA Berg,V...
In relation to biohydrogen production and redox poise of the cell when the carbon source is the acetate, the ethylmalonyl-CoA pathway has some disadvantages. First, the pathway requires ATP and reducing power in the form of NADPH2, which thereby diminishes energy and the electron output of the ...
(2009). (2S)-methylsuccinyl- CoA dehydrogenase closes the ethylmalonyl-CoA pathway for acetyl-CoA assimilation. Mol Microbiol 73: 992-1008.Erb TJ, Fuchs G, Alber BE. (2009). (2S)-Methylsuccinyl-CoA dehydrogenase closes the ethylmalonyl-CoA pathway for acetyl-CoA assimilation. Mol Microbiol 73...
Analysis of C positional enrichment in glycine by NMR was consistent with the predicted labeling pattern as a result of the operation of the ethylmalonyl-CoA pathway and the unique operation of the latter for glyoxylate generation during growth on methanol. The results also revealed that 2 ...
Bill, N., Tomasch, J., Riemer, A., Muller, K., Kleist, S., Schmidt-Hohagen, K., et al. (2017). Fixation of CO2 using the ethylmalonyl-CoA pathway in the photoheterotrophic marine bacterium Dinoroseobacter shibae. Environ. Microbiol. 19, 2645-2660. doi: 10.1111/1462-2920.13746...
Metabolite profiling of CoA esters involved in the ethylmalonyl-CoA pathway (EMCP).Patrick KieferMarkus BuchhauptPhilipp ChristenBjörn KaupJens SchraderJulia A. Vorholt
Here we discuss the history of CCRs in both primary and secondary metabolism, the mechanism by which they function, examples of new polyketide diversity from pathway specific CCRs, and the role of CCRs in facilitating the bioengineering novel polyketides.Wilson, M....