Visual field tests showed bilateral centrocecal scotoma, and colour vision was abnormal, with bilateral deuteranopia. Suspecting drug-related optic neuropathy, ethambutol was withdrawn but his visual acuity did not improve. His optic discs became progressively paler, eventually presenting as bilateral ...
We defined the ethambutol induced ocular toxicity as stastically siginificant change of visual function which was induced by ethambutol.Objective: We aimed to identify a visual function test for the early detection of subclinical ethambutol-induced ocular toxicity. Furthermore, we also investigated the...
chiasmal toxicityEthambutol is a well recognized antimicrobial agent used as a first line agent in the treatment of tuberculosis. Optic neuropathy is a known complication of ethambutol therapy. Rarely, chiasmal ethambutol toxicity may manifest as a bitemporal visual field deficit. We report an ...
Various tests, such as fundus examination, visual field tests, and electroretinograms, were conducted to assess the extent of the cone dysfunction. The article concludes that ethambutol can cause not only optic nerve toxicity but also cone dysfunction, and physicians should be aware of t...
An event is serious (FDA MedWatch definition) when the patient outcome is: death life-threatening hospitalisation disability congenital anomaly requires intervention to prevent permanent impairment or damage A 70-year-old woman developed chiasmal toxicity with bitemporal hemianopia during treatment with ...
Conclusion: Pattern-VER and visual field examinations are sensitive tests to detect early toxicity. Together with OCT, they may help to identify patients who are likely to develop clinical toxicity.VDrMenonDrDDrJainDrRDrSaxenaDrRDrSoodDr
visual fieldOCULAR TOXICITYVISUAL FUNCTIONThe extended use of ethambutol beyond 2 months for treating tuberculosis has increased risk of optic neuropathy. We performed a systematic review of studies evaluating optic neuropathy in extended ethambutol use since 2010 and compared the outcome with a similar ...
At the time when visual acuity was normal there was still electrophysiological evidence of a mild involvement of the anterior visual pathway. The papillomacular bundle seems to be especially involved in ethambutol eye toxicity.doi:10.1016/0168-5597(88)90073-1J.E. Petrera...
chiasmal toxicityEthambutol is a well recognized antimicrobial agent used as a first line agent in the treatment of tuberculosis. Optic neuropathy is a known complication of ethambutol therapy. Rarely, chiasmal ethambutol toxicity may manifest as a bitemporal visual field deficit. We report an ...
Visual evoked responseObjective:The study was conducted to evaluate the ocular toxicity of ethambutol given in both intensive and continuation phases of treatment in children with drug-sensitive tuberculosis. Methods:A prospective study of 94 eyes from 47 patients receiving an ethambutol-containing ...