Breast Cancer Res Treat. 2008; 108 :351–61.Levin ER, Pietras RJ. Estrogen receptors outside the nucleus in breast cancer. Breast Cancer Res Treat. 2008; 108 :351–361.Levin ER, Pietras RJ. Estrogen receptors outside the nucleus in breast cancer. Breast Cancer Res Treat. 2007...
G. Ribeiro MD, DMRT, FRCR - 《Cancer》 被引量: 467发表: 1980年 Prognostic value of estrogen and progesterone receptors in primary breast cancer Estradiol receptor alone or estradiol and progesterone receptors (ER, PgR) have been measured in tumors from 307 women whowere treated for primary ...
Thus, the hormone receptors in these tumors can be functionally active and used for therapeutic intervention. This proposal has been questioned in some studies because estrogen dependent proteins are expressed to a lesser degree in men. Furthermore, men do not have a better overall breast cancer ...
The estrogen receptor (ER) is the single most powerful predictor of breast cancer prognosis as well as an important contributor to the biology of carcinogenesis. In addition, endocrine therapy targeting ER directly (SERMS) or indirectly (aromatase inhibitors) forms the mainstay of adjuant therapy....
Estrogen Receptors in Human Breast Cancerdoi:10.1038/bjc.1976.31ous SknnrCROSSREFBritish Journal of Cancer
The human epidermal growth factor receptor 2 (HER2) is overexpressed in 13–22% of breast cancers (BC). Approximately 60–70% of HER2+ BC co-express hormone receptors (HRs). HR/HER2 co-expression modulates response to both anti-HER2–directed and endo
Plasma sex hormone binding globulin and tumor estrogen receptor status in breast cancer patients Certain commonly taken pharmaceutical preparations induce increased levels of plasma prolactin. The effects of these drugs on (a) tumor steroid receptors a... R Mason,W Miller,R Hawkins,... - 《Lancet...
In MCF-7 human breast cancer cells about 75% of the cell's total estrogen receptor sites were unexpectedly found in nuclei not bound with estrogens [13]. These findings were based on studies with crude nuclei and it was originally proposed that these unfilled nuclear estrogen receptors might be...
Bone metastasis is a prominent cause of morbidity and mortality in cancer. High rates of bone colonization in breast cancer, especially in the subtype expressing estrogen receptors (ERs), suggest tissue-specific proclivities for metastatic tumor formation. The mechanisms behind this subtype-specific or...
Cancer 46(12 Suppl): 2765-2769, 1980 Google Scholar Saez S, Cheix F, Asselain B: Prognostic value of estrogen and progesterone receptors in primary breast cancer. Breast Cancer Res Treat 3: 345-354, 1983 Google Scholar Von Maillot K, Horke W, Prestele H: Prognostic significance of ...