Sommer, S, Fuqua, SA (2001) Estrogen receptor and breast cancer. Semin Cancer Biol 11: pp. 339-352Sommer S.; Fuqua S. A. W. Estrogen Receptor and Breast Cancer. Semin. Cancer Biol. 2001 , 11 , 339–352.Sommer S, Fuqua SA 2001 Estrogen receptor and breast cancer. Semin Cancer ...
The selective estrogen receptor modulators (SERM) are compounds with mixed ER mediated agonist and antagonist activity, depending on tissue, ER subtype and presence of co-factors. The most well known SERM is tamoxifen, used primarily in adjuvant and palliative treatment of breast cancer. Tamoxifen ...
Estrogen receptor (ER) and progesterone receptor (PR) testing are performed in the evaluation of breast cancer. While the clinical utility of ER as a predictive biomarker to identify patients likely to benefit from hormonal therapy is well-established, the added value of PR is less well-defined...
Microscopic review of 490 consecutive human breast biopsy and mastectomy specimens were correlated with estrogen and progesterone receptor content of the tissue, by subtype and degree of differentiation. Of the 4 grades of differentiation, the less differentiated Grade III and IV tumors showed significant...
10.The Role of Epidermal Growth Factor Receptor Signaling Pathway in Endocrine Therapy to Estrogen-dependent Breast Cancer;表皮生长因子受体信号通路在激素依赖性乳腺癌内分泌治疗中的作用 11.Curcumin-induced the Apoptosis of Androgen-dependent and Androgen-independent Prostate Cancer Cell Lines in Vitro;姜黄...
Identification of the second human estrogen receptor, the estrogen receptor β (ERβ), prompted us to evaluate its role in breast cancer. We studied the expression of ERβ by immunohistochemistry and mRNA in situ hybridization in 92 primary breast cancers and studied its association with ERα, ...
Estrogen receptor positive breast cancers and their association with environmental factors. Int J Health Geograp. 2011; 10 :32.St-Hilaire S, et al. Estrogen receptor positive breast cancers and their association with environmental factors. Int J Health Geogr. 2011;10:e32....
Breast cancer is the most common cancer in women worldwide with more than 500,000 new cases diagnosed and 250,000 deaths annually. Treatment directed to inhibiting the action of the estrogen receptor (ER) represents one of the earliest examples of a successful targeted therapy for clinical breas...
Membrane-Initiated Steroid Signaling Action of Estrogen and Breast Cancer. Although classical concepts had assigned priority to the nuclear-initiated steroid signaling pathway of estrogen receptor (ER), recent studies document tha... R Song - 《Seminars in Reproductive Medicine》 被引量: 38发表: 2007...
Targeted therapies against breast cancer, such as those aimed at estrogen receptor α (ERα) or the Her2 receptor tyrosine kinase, have shown some levels of success [1],[2]. However, clinical observations also indicate that tumors that initially respond to targeted therapies often relapse and ...