K. Estrogen-induced breast cancer: alterations in breast morphology and oxidative stress as a function of estrogen exposure. Toxicol. Appl. Pharmacol. 232:78-85; 2008.Mense S, et al. Estrogen-induced breast cancer: alterations in breast morphology and oxidative stress as a function of estrogen ...
10.The Role of Epidermal Growth Factor Receptor Signaling Pathway in Endocrine Therapy to Estrogen-dependent Breast Cancer;表皮生长因子受体信号通路在激素依赖性乳腺癌内分泌治疗中的作用 11.Curcumin-induced the Apoptosis of Androgen-dependent and Androgen-independent Prostate Cancer Cell Lines in Vitro;姜黄...
Our data also suggest that BCAR3 may play a favorable role in preventing disease progression in breast cancer patients. BCAR3 antagonizes TGFβ-induced Smad phosphorylation and accumulation of phospho-Smad3 in the nucleus We then sought to investigate the molecular mechanisms by which BCAR3 exerts ...
PI3K inhibition (PI3Ki) can restore dependence on ER signaling for some hormone therapy-resistant ER+breast cancers, but is ineffective in others. Here we show that short-term supplementation with estrogen strongly enhancedinduced mammary tumorigenesis in mice that resulted exclusively in ER+tumors, ...
Proteomic Analysis of Pathways Involved in Estrogen- Induced Growth and Apoptosis of Breast Cancer Cells.doi:10.1371/journal.pone.0020410Background: Estrogen is a known growth promoter for estrogen receptor (ER)-positive breast cancer cells. Paradoxically, in breast cancer cells that have been ...
Abstract 582: Superoxide dismutase 3 is induced by antioxidants, inhibits oxidative DNA damage, and is associated with inhibition of estrogen-induced breast cancer B Singh,HK Bhat - 《Cancer Research》 被引量: 0发表: 2012年 Redox regulation in cancer Oxidative stress, implicated in the etiology ...
2) hormone refractory prostate cancer 激素非依赖性前列腺癌 1. Influence of endothelin-1 on apoptosis induced by paclitaxel in hormone refractory prostate cancer cell line PC3; 内皮素-1对紫杉醇诱导激素非依赖性前列腺癌细胞PC3凋亡的影响 2. Objective:To investigate the effects of the epidermal ...
Moreover, overexpression of Cyr61 in MCF-12A normal breast cells induced their tumor formation and vascularization in nude mice. In summary, these results suggest that Cyr61 may play a role in the progression of breast cancer and may be involved in estrogen-mediated tumor development. 展开 ...
CIAPIN1 confers multidrug resistance by upregulating the expression of MDR-1 and MRP-1 in gastric cancer cells In a previous study, we observed that cytokine-induced apoptosis inhibitor 1 (CIAPIN1), a newly identified apoptosis inhibitor, was upregulated at the mRNA... Z Hao,X Li,T Qiao,...
Although paradoxical because estrogen is recognized to stimulate breast cancer growth, laboratory data support a mechanism of estrogen-induced apoptosis under the correct environmental circumstances. Long-term antiestrogen treatment or estrogen deprivation causes the eventual development and evolution of anti...