Estrogen and breast cancerReports on the effect of hormone therapy on the risk of breast cancer. Importance of assessing the trade-offs between the risks and benefits of hormone for each patient.Consumer Reports on Health
Alcohol, estrogen, and breast cancer.Alcohol, estrogen, and breast cancer.Looks at several studies on the relationship of alcohol consumption, postmenopausal estrogen, and breast cancer. Higher risks of breast cancer in both estrogen users and moderate drinkers; Limitations of the studies; Theories on...
When we added oophorectomy status as a covariate in the analyses of CEE alone and breast cancer mortality over the cumulative 18 years of follow-up, the HR changed minimally from 0.55 to 0.54. Other risk factors for breast cancer also were well balanced between the 2 randomized groups at ...
Based on information from known breast cancer risk factors, animal experimentation, and studies of hormone levels in high and low risk populations, it is widely believed that pituitary-gonadal hormones, especially estrogen, play a role in the pathogenesis of breast cancer. A potential risk for brea...
In Dr. Korenman's review (March 29, p. 700) of the estrogen window hypothesis in the etiology of breast cancer, he uses the term "promotor" to describe a process whereby a tissue is rendered more susceptible to a carcinogen through the variable expression of hormones. This individual variab...
Breast Cancer and Estrogen Therapy 来自 Semantic Scholar 喜欢 0 阅读量: 13 作者: V Blair 摘要: To the Editor. —In 1991, THE JOURNAL published1 a meta-analysis on the effects of estrogen replacement therapy on the risk of breast cancer. Data for the analysis were extracted from 18 publishe...
Bulun SE, Price TM, Aitken J, Mahendroo MS, Simpson ERA link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain ... SE Bulun,TM Price,J Aitken,... - 《Journal of Clini...
Breast cancer ranks no. 1 in women cancer worldwide, while 60–70% are estrogen receptor alpha positive. The estrogen selective modulators, such as tamoxifen, become the effective drugs for controlling ER alpha breast cancer progression. However, tamoxif
Breast Cancer PatientEstrogen Status ReceptorAsian WomanPremenopausal PatientBACKGROUND: The incidence of breast cancer in Singapore, reflecting cancer trends of ... SE Lim,M Back,E Quek,... - 《World Journal of Surgery》 被引量: 117发表: 2007年 Estrogen and progesterone receptors in breast canc...
Similarly, it was shown that, inhibition of ERα signaling stimulates autophagosome formation and flux in ER+ breast cancer cells [48]. This might be a feedback mechanism to put a tight leash on autophagy by mTOR-regulated ER phosphorylation and anti-estrogen resistance [49]. However, mis...