Menopausal estrogen use and the risk of breast can- cer. Breast Cancer Res Treat 1986; 7: 193-9.McDonald, JA, Weiss, NS, Daling, JR, Francis, AM, Polissar, L (1986) Menopausal estrogen use and the risk of breast cancer. Breast Cancer Res Treat 7: pp. 193-9...
As ER-HER2 crosstalk has been implicated in the development of resistance to both endocrine and HER2-directed agents32,33,34, published preclinical and clinical research suggest a potentially greater benefit for dual- versus single-receptor targeting of HR+/HER2+ breast cancer7,23,35,36. Benefits...
Gastro Symptoms of Menopause May Vary by Race Dec. 8, 2021 New Hormonal Pill May Boost Outcomes for Older Breast Cancer Patients Dec. 7, 2021 PTSD Symptoms May Vary Throughout Menstrual Cycle: Study Oct. 28, 2021 Fertility Drugs Won't Raise Breast Cancer Risk ...
there are many food health products on the market, some health care products contain a certain amount of hormones, after eating can stay young, but we want to remind everyone that these hormones can promote tumorigenesis, so in order to prevent and treat breast cancer diseases, it is necessary...
6.9 years) was elevated approximately twofold but declined after 2002; HRs were 1.0 in 2003 and 2004. HT use by these women declined after announcement of the clinical trial findings in 2002, and subsequent incidence of breast cancer dropped among participants who had entered the study as HT us...
Tamoxifen resistance is a major problem in the treatment of estrogen receptor (ER) α -positive breast cancer patients. Although the mechanisms behind tamoxifen resistance are still not completely understood, clinical data suggests that increased express
16-alpha-hydroxyestrone (16-OH): These are potentially harmful and are associated with an increased risk of breast cancer. The metabolism of these estrogens is largely dependent on the health and efficiency of your liver and the digestive tract, though genetics do play a role as well. ...
Advanced breast cancers represent a major therapeutic challenge due to their refractoriness to treatment. Cancer-associated fibroblasts (CAFs) are the most abundant constituents of the tumor microenvironment and have been linked to most hallmarks of canc
Estrogen receptor alpha (ER alpha) is expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression. ER alpha positive breast cancer can be well controlled by ER alpha modulators, such as tamoxifen. However, tamoxifen resistance is commonly observed by altered ER alph...
Disease of the Breast. W.B. Saunders Company: Philadelphia, London, Toronto, Mexico City, Rio de Janeiro, Sydney, Tokyo, Honk Kong, 1986, pp 267–283. Google Scholar Dixon JM . Cystic disease and fibroadenoma of the breast: natural history and relation to breast cancer risk. Br Med ...