Estrogen deprivationAdverse eventsHormone receptor (HR) positiveLuminal breast cancerIndividualization of treatment is crucial. Consideration should be given to therapy effects on quality of life, and strategies for controlling associated symptoms should be offered....
and decreases pain with intercourse. In women with contraindications to systemichormone therapyor who need treatment only for urogenital atrophy, local therapy such as with an estrogen cream, ring, or tablet might be considered. Vaginal estrogens have a profound local estrogenic effect on the urogenit...
menopause before age 45 is sometimes referred to asearly menopause. Early or premature menopause may be induced if theovariesare surgically removed (for example, in ahysterectomyor intreatmentof ovarian cancer) or incidentally damaged or destroyed (as a side effect ofradiation therapyor chemotherapy)...
Combined hormone therapy is reported to increase breast cancer risk, whereas the use of estrogen therapy only has no effect on risk, whereas some studies suggest a small risk or decrease risk (reviews: Chlebowski and Anderson, 2014; Lobo, 2017). A recent meta-analysis reported that estrogen ...
Remove the cap from the tube of cream. Screw the nozzle end of the applicator onto the open end of the tube. Gently squeeze the tube from the bottom to fill the applicator with the amount of cream that your doctor has told you to use. Look at the markings on the side of the applica...
Estrogen derivatives may be combined with another class of medication known as selective estrogen receptor modulator (SERM). SERMs have estrogen-like effects on bone, increasing its density, but have antiestrogenic effects in the breast anduterus, which reduces the risk ofendometrial hyperplasia(thicke...
The study did not evaluate the effects of CE or CE/MPA on menopausal symptoms. The CE/MPA substudy was stopped early because, according to the predefined stopping rule, the increased risk of breast cancer and cardiovascular events exceeded the specified benefits included in the "global index."...
My mom has had ongoing problems with low estrogen because she is going through menopause. Her doctor recently put her on bioidentical hormones. The come in a tray and are kind of like chewy candy in consistency. She says they taste like something much worse than candy, though. ...
In this phase III crossover trial, 150 breast cancer survivors with HSDD received 2% testosterone versus placebo cream for 4 weeks. Testosterone cream achieved higher serum levels of bioavailable testosterone, but no positive effect on libido was demonstrated.158 In addition to concerns about ...
More serious side effects of estrogen blockers, especially when used for prolonged periods of time, may include the development of blood clots, allergic reactions, or an increased risk of developing cancer of the reproductive organs. Most side effects of estrogen blockers are relatively mild and ...