A method of estimating the elimination half-life of a drug at any selected serum concentration when the Km and Vmax of that drug are known is described. The method was validated in six patients by determining their Km and Vmax values for phenytoin, using data obtained at two serum ...
The method proposed here consists of a continuously flowing hydroponic system and a method of data analysis that estimates a value of Kmand Vmax for each plant. The method is nondestructive; it does not require large amounts of space; and the plants are near steadystate uptake. In simulated ...
Examining enzyme kinetics is critical for understanding cellular systems and for using enzymes in industry. The Michaelis-Menten equation has been widely used for over a century to estimate the enzyme kinetic parameters from reaction progress curves of substrates, which is known as the progress curve...
2 · Wang‑Cheol Song3 Published online: 21 May 2019 © The Author(s) 2019 Abstract In Internet of Vehicles (IoV), numerous routing metrics have been used to assess the per- formance of routing protocols such as, packet delivery ratio, throughput, end-to-end delay and path ...
Vmax Electrical speed of the rotor of permanent magnet synchronous motor Number of pole pairs for the permanent magnet synchronous motor Electrical position of the rotor of permanent magnet synchronous motor Reference control torque (Tcont in Figs. 2, 3) Reference torque current component Three phase...
A method of estimating the elimination half-life of a drug at any selected serum concentration when the Km and Vmax of that drug are known is described. The method was validated in six patients by determining their Km and Vmax values for phenytoin, using data obtained at two serum ...
The Kmand Vmax values for total bilirubin glucuronide formations were determined to be 0.05 ± 0.01 μM and 181.9 ± 5.3 pmol/min/mg-protein, respectively, in human recombinant UGT1A1, and 0.23 ± 0.05 μM and 875 ± 45 pmol/min/mg protein in human liver microsomes (HLM).Conclusion: ...
The results obtained from the plots generated were: 35.50gmol/l.hr for the velocity of reaction of the enzymes (Vmax), 0.10049hr-1for the maximum specific growth rate (碌max) 826.45gmol/l for the Michaelis-Menten constant (Km), 0.005402577 for maintenance coefficient (Ms), 10.104kgCx/kgCs...
(ii) No significant difference in Vmax was found between cellulases and ligninases; however, there was significant difference in Km between them. (iii) Ligninases had higher Ea values and lower pHopt than cellulases; average ratio of pHsen to pHopt ranged 0.3–0.4 for the five enzymes,...
To our knowledge, this is the first effort to determine both Vmax and Km kinetic parameters describing the biotransformation of phenanthrene- and anthracene-analogue azaarenes. The results show that the rate of removal of azaarenes from contaminated soil will probably be rather high, although ...