上一节我们讲到CRISPR数据分析流程:CRISPR实验设计与NGS数据分析,CRISPR数据的分析,最终获取的是不同样本中sgRNA counts值。基于以上假设,作者通过定义CRISPR gene score来评估genes是否为essential genes,即gene score(CS)值越低,表明其final sgRNA counts相比于initial sgRNA ...
CEG: a database of essential gene clusters . BMC genomics 14 , 769 (2013).Ye,Y.N., Hua,Z.G., Huang,J., et al. (2013) CEG: a database of essential gene clusters. BMC Genomics, 14, 769.Ye Y-N, Hua Z-G, Huang J, Rao N, Guo F-B. CEG: a database of essential gene ...
网络基因;必需基因 网络释义 1. 基因 基因(essentialgene).但以必要基因作为癌症治疗pub.chinasciencejournal.com|基于1 个网页 2. 必需基因 利用RNAi技术,可方便快捷地将基因分为必需基因(essentialgene)和非必需基因(nonessentialgene)。若RNAi使靶向mRNA沉默后 …conference.haoyisheng.com|基于1 个网页...
Here, we will discuss these findings and highlight the mechanisms underlying the ability of cells to survive an essential gene deletion. Also, since essential genes are prioritized as targets for anticancer therapy, we discuss emergence of bypass resistance mechanisms toward targeted therapies as the ...
必需基因(essential gene) :一些基因在突变时会引起致死表型,这些基因被称为必需基因。以下为句子列表: 英文: Cloning of Essential Gene NCED3 for Drought Stress by TAIL-PCR Method in Arabidopsis Thaliana 中文: 利用TAIL-PCR方法克隆拟南芥干旱主效基因NCED3 更详细... 英文: Characterization of The Essenti...
Both gene sets were enriched in neurodevelopmental disorders, but only NEGs were robustly associated with neuropsychiatric disorders risk genes. Finally, NEGs were more likely to show differential expression in the brains of neuropsychiatric disorders patients than ACEGs. Overall, genome-wide central ...
出版者:Jones & Bartlett Learning 作者:Jocelyn E. Krebs 出品人: 页数:850 译者: 出版时间:2012-1-10 价格:USD 172.95 装帧:Paperback isbn号码:9781449644796 丛书系列: 图书标签:生物科学gene Lewin's Essential Genes 2025 pdf epub mobi 电子书 图书描述 ...
essential gene【生化】分享到: 必需基因分类: 科技词汇 | 查看相关文献(pubmed) | 免费全文文献 详细解释:以下为句子列表:分享到: 赞助商链接 你知道它的英文吗? ·必需氨基酸 ·本质边界条件 ·必备条件 ·本质常数 ·本质收敛 ·必需元素 ·必需□ ·必需脂肪酸 你知道中文意思吗? ·...
(2007)). iPS generated by reprogramming are similar to human ES cells in morphology, the capacity for unlimited proliferation, surface-antigen expression, gene expression, the ability to differentiate into cell types representing the three germ layers in vitro, and the ability to form teratomas ...
In ePath, gene essentiality is linked to biological functions annotated by KEGG Ortholog (KO). Two new scoring systems, namely, E_score and P_score, are proposed for each KO as the EG evaluation criteria. E_score represents appearance and essentiality of a given KO in existing experimental ...