Dystrophin associates with a number of peripheral and membrane-bound proteins designated as the dystrophin-glycoprotein complex (DGC). Identification of the integral components of the DGC was defined on the basis of four distinct biochemical and cellular characteristics, which eliminated less-tightly ...
Plasma markers have been continuously advocated as pointers to estimate the long-term risk of cardiovascular disease in the general population. We examined the relationship between plasma high-sensitivity C-reactive protein (hs-CRP), homocysteine (Hcy), high-sensitivity cardiac troponin T (hs-cTnT)...
Munakata M, Imai Y, Takagi H, Nakao M, Yamamoto M, Abe K. Al- tered frequency-dependent characteristics of the cardiac baroreflex in essential hypertension. J Auton Nerv Syst. 1994;49:33-45.Munakata, M., Imai, Y., Takagi, H., Nakao, M., Yamamoto, M., and Abe, K. Altered ...
Clinical Characteristics of Hypertensive Patients and Normotensive Controls Age (years) Male (%) Body mass index (kg/m2) Smoking habit (%) Hyperlipidemia (%) Diabetes mellitus (%) Statin therapy (%) Fibrate therapy (%) Insulin therapy (%) Systolic blood pressure (mmHg) Mean blood pressure (...
There was no difference in the levels of cTnI between male and female normotensive subjects. Serum CK-MB activity was higher in female than male hypertensive subjects. In the light of these results, cardiac markers should be routinely done in the evaluation of hypertensive subjects and sex-...
Our data suggest that Ntep is an essential regulator of a wide range of fibroblast characteristics. To corroborate our findings in primary cells, we isolated mouse embryonic fibroblasts (MEFs) at E13.5 and tested the effects of Ntep knockdown. Ntep was efficiently silenced by GapmeR treatment. ...
Traumatic Brain Injury (TBI) represents one of the main causes of brain damage in young people and the elderly population with a very high rate of psycho-physical disability and death. TBI is characterized by extensive cell death, tissue damage and neuro-inflammation with a symptomatology that va...
Vitamin D diverts the release characteristics of mast cells to produce and excrete IL-10 without inducing degranulation of pro-inflammatory mediators [138]. IL-10 is an important anti-inflammatory cytokine that inhibits the production of pro-inflammatory cytokines, such as IFN-γ, IL-2, IL-3,...
Recent studies showed that proteinuria is also a risk factor for cardiac and cranial vascular events. The glomerulus, a tiny, ball-shaped structure composed of capillaries, is a filtration unit of the kidney, and the glomerular capillary wall functions as a barrier, preventing the leakage of ...
Baseline Clinical Characteristics After fasting overnight, BP was measured with an appropriate arm cuff and a mercury column sphygmomanometer on the left arm after a resting period of at least 10 min in the supine position. After BP measurement, venous blood sampling was performed in all subjects...