Each spectrum represents the abundance and m/z data from one voxel sampled, which then corresponds to a pixel in the ion image. Ion images are generated as heat maps of the abundance of a chosen m/z, allowing relative quantification of analytes. The resulting localization information can ...
LC-ESI-HRMS在化合物结构研究中的应用
The ESI-HRMS/MS spectrum of the deprotonated molecule yielded a major MS/MS fragmentation ion at m/z 769.09, 617.0, and 169.01 that corresponding to the losses of gallate unit (−170 Da) and a galloyl residue (−152 Da). According to the literature data (Cantos et al., 2003) this...
Further developments in CE-ESI-MS can help to understand cell heterogeneity during normal brain function and disease states, such as Autism spectrum disorder.Eric J. CorcoranMarta ZamarbideM. Chiara ManziniPeter NemesProceedings 64th Annual ASMS Conference on Mass Spectrometry and Allied Topics, Vol....
A van Krevelen diagram is a common approach for visualizing and evaluating data sets generated by the HRMS analysis of complex mixtures (Kew et al., 2017; Kim et al., 2003). In Fig. 4, the x-axis is the O/C ratio, so formulae with higher oxygen numbers trend towards the right. Th...
We began ESI-IM-MS analysis by first assigning all the peaks in each spectrum to specific Aβ oligomers (see Supplementary Text). Briefly, assignments were performed on the basis of the 13C isotope distribution (Fig. 3b,c and Supplementary Figs S3b,c–S5b,c), as proposed in the ...
Electrospray ionization-mass spectrometry (ESI-MS) is used to analyze metal species in a variety of samples. Here, we describe an application for identifying metal species by tandem mass spectrometry (ESI-MS/MS) with the release of free metals from the corresponding metal–ligand complexes. The ...
PNMR,ES-MS和HRMS等方法确认.合成路 线及化合物的结构如Scheme1所示. 1.3质谱条件 电喷雾多级质谱(ES-MS n )分析在BrukerEs uire-LC离子阱质谱仪上进行.样品溶于甲醇,然后 a:R=—CH 3 ;b:R=CH 2 COOCH 3 ;c:R=—CH 2 CH(CH 3 )
2.5. UPLC-ESI-HRMS/MS analysis LC-MS analyses were performed on an Acquity UPLC system class H (Waters, St. Milford, MA, USA) composed of a PDA detector, sample manager and a quaternary solvent manager as well as an Acquity UPLC BEH C18 column (St. Milford, MA, USA; 130 Å, 1.0...
LC-ESI-HRMS在化合物结构研究中的应用