In the present work, we demonstrated that VPS28 (Vacuolar Protein Sorting-associated protein 28), an ESCRT-I protein, is a new Gβγ-interacting partner and tested the hypothetical role of the complex formed by these previously unrelated proteins in the organization of the mitotic spindle. 2....
说起分泌和转运,不得不提转运所需的内涵体分选复合体 (Endosomal sorting complex required for transport, ESCRT)。ESCRT 是一个蛋白家族,在 MVBs 膜上连续结合复合物 (ESCRT-0, -I, -II 和 -III),其中 ESCRT-0 通过泛素化依赖途径调控内容物聚集,ESCRT-I 和 ESCRT-II 诱导芽的形成,ESCRT-III 驱动小泡的...
The endosomal sorting complex required for trans- port (ESCRT-I) is a 350-kDa complex of three proteins, Vps23, Vps28, and Vps37. The N-terminal ubiquitin-conjugating enzyme E2 variant (UEV) domain of Vps23 is required for sorting ubiquitinated proteins into the internal vesicles of multives...
Furthermore, we present data which support a model in which the Vps23-containing protein complex, ESCRT-I, recognizes ubiquitinated cargo. Taken together, these data suggest that a subset of the Vps class E proteins initiate ubiquitin-dependent MVB sorting by selectively binding ubiquitinated cargo ...
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ESCRT (endosomal sorting complex required for transport) complexes orchestrate efficient sorting of ubiquitinated transmembrane receptors to lysosomes via multivesicular bodies (MVBs). Yeast ESCRT-I and ESCRT-II interact directly in vitro; however, this association is not detected in yeast cytosol. To ga...
Flotillin-1 depletion impairs cargo delivery from ESCRT-0 During sorting, the cargo delivery from ESCRT-0 to ESCRT-I is mediated by the interaction of Hrs and Tsg101.12 Our data show that flotillin-1 interacts with both Hrs and Tsg101, which might implicate a role in cargo transfer between ...
百度试题 结果1 题目将所有字母组成正确的英语单词,并写出其汉语意思1.mecara 2.escrte 3.iskp 4.ewnpepar 5.sione 6.iwdny 7.ardw 8.esek 9.rdikn 相关知识点: 试题来源: 解析 camerasecretskipnewspapernoisewindydrawseekdrink反馈 收藏
曹荣目前担任南昌依诺思实业有限公司、温江区悦可丽丽商贸部法定代表人,同时担任禧跃(广州)文化传媒有限公司监事,南昌依诺思实业有限公司执行董事,总经理;二、曹荣投资情况:曹荣目前是南昌依诺思实业有限公司直接控股股东,持股比例为90%;目前曹荣投资南昌依诺思实业有限公司最终收益股份为90%,投资温江区悦可丽丽商贸部最终收益...
RNA viruses (e.g. HIV Gag) promotes release of virus from the cell by recruiting the ESCRT machinery to the viral budding sites at the plasma ... MJ Clague,S Urbé - 《Trends in Cell Biology》 被引量: 145发表: 2003年 Ubiquitylation of MHC class I by the K3 viral protein signals ...