AmpCCarbapenemaseD72CPurpose The MAST? D72C test is a phenotypical test which can detect ESBL and AmpC production in Enterobacterales. It can also identify the suspected presence of carbapenemase. The aim of the present study was to assess the sensitivity and specificity of this test and to ...
多数产esbl大肠埃希菌和克雷伯菌属对头霉素类敏感,但耐药率高于碳青霉烯类和头孢哌酮/舒巴坦和哌拉西林/他唑巴坦,此可能与其他机制有关,如外膜孔蛋白得缺失或同时产ampc酶有关。头霉素类易于诱导细菌产生诱导酶,而且对诱导酶不稳定,进而发生耐药。因此,头霉素类仅用于产esbl菌株所致的 28、轻中度感染的治疗...
目前ESBLs表型检测方法的测定结果不能全面反映肠杆菌科细菌对头孢类菌素的耐药性,其它耐药机制如产AmpC酶、碳青霉烯酶、外膜孔蛋白丢失等均会干扰ESBLs的检测结果。动物感染模型、药代动力学以及部分临床病例研究资料表明,与临床疗效相关的是细菌最低抑菌浓度(MICs),而不是耐药机制。2010年CLSI下调了大部分头孢菌素对...
BLIsversuscarbapenems,stratifiedbyriskofbiasinallocationconcealmentPT,piperacillin/tazobactamTC,ticarcillin/clavulanate;CS,cefoperazone/sulbactamAS,ampicillin/sulbactamE,ertapenemI,imipenemM,meropenemC,carbapenem-abdominal/pelvicinfections(11trials)-febrileneutropenia(8)-LRTIs(7)-cSSTIs(4)-UTIs(2)β-Lactam/β...
Meta-analysis of the prevalence of ESBL-producingEnterobacteriaceae, stratified by infection source (nosocomial versus community-acquired infections). The analysis indicates no statistically significant difference between the two sources, with aP-value of 0.68 ...
ConcerningC. diversusisolates, they were highly sensitive to Ceftriaxone (100%), Amikacin (95.5%), and Imipenem (95.5%). Sami et al. found thatCitrobacterspecies isolated from UTI patients were sensitive to Imipenem (100), Amikacin (85.2%), and Gentamicin (77.4%), which is consistent with ...
Activity of temocillin against prevalent ESBL- and AmpC-producing Enterobacteriaceae from south-east England aModal values are indicated in boldface.bIn addition to the species groups detailed, this total also includes two Hafnia spp. and one Pantoea sp. with hype... DM Livermore,R Hope,EJ Fagan...
Carbapenems versusalternative antibiotics for the treatment of bacteraemia due toEnterobacteriaceae producing extended-spectrum B -lactamase 59、s: a systematic review and meta-analysis. J Antimicrob Chemother 2012; 67: 2793- 2803.2、社区获得血流感染:俞云松、周志慧产 ESBL 细菌引起的社区发作血流感染( ...
Shnaiderman-Torban A, Navon-Venezia S, Dor Z, Paitan Y, Arielly H, Ahmad WA, et al. Extended-spectrum β-lactamase-producingEnterobacteriaceaeshedding in farm horses versus hospitalized horses: prevalence and risk factors. Animals (Basel). 2020.https://doi.org/10.3389/fmicb.2019.02488. ...
87.5 % for the CLSI method, and only 73.1 % for D68C, which, however, reached 92.1 % if the strains for which supplementary investigations were recommended and the complex mutant TEM (CMT)-producing strains were excluded versus 94.1 % and 88.2 % for the other methods. ...