Kasaai, B.; Caolo, V.; Peacock, H.M.; Lehoux, S.; Gomez-Perdiguero, E.; Luttun, A.; Jones, E.A.V. Erythro-myeloid progenitors can differentiate from endothelial cells and modulate embryonic vascular remodeling. Sci. Rep. 2017, 7. [CrossRef] [PubMed]...
Erythro-myeloid progenitors: “definitive” hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells. Blood Cells Mol. Dis. 51, 220–225 (2013). Article PubMed Google Scholar Mass, E. et al. Specification of tissue-resident macrophages during organogenesis. Science 353,...
Erythro-myeloid progenitors (EMP) serve as a major source of hematopoiesis in the developing conceptus prior to the formation of a permanent blood system. In this review, we summarize the current knowledge regarding the emergence, fate, and potential of this hematopoietic stem cell (HSC)-independe...
We have shown that early erythro-myeloid progenitors (EMPs), late EMPs, and definitive hematopoietic stem cells (HSCs) each gave rise to mast cells in succession via an intermediate integrin β7+ progenitor. From late embryogenesis to adult, early EMP-derived mast cells were largely replaced by...
The marrow can range from hypocellular to hypercellular and the myeloid to erythroid ratio is variable. Because HLH commonly occurs secondary to infection or a neoplastic process, the bone marrow may be concurrently involved by the inciting process, such as a lymphoma (Box 13.2). Other abnormal...
(Fig.3f). The number of multi-potent progenitors (MPP) and granulocytic-macrophage progenitors (GMP) was also reduced, common myeloid progenitors (CMP) were less affected, and the number of other progenitors (pre-GM, pre-MegE, MkP) did not significantly differ from littermate controls (...
Amifostine (AMF) promotes in vitro growth and survival of hematopoietic progenitors. In this study we evaluated the efficacy of AMF in the treatment of ane... N Viniou,E Terpos,A Galanopoulos,... - 《Annals of Hematology》 被引量: 44发表: 2002年 Mutation spectrum in Chinese patients affe...
Here we show that a complementary source of endothelial cells is recruited into pre-existing vasculature after differentiation from the earliest precursors of erythrocytes, megakaryocytes and macrophages,聽the聽erythro-myeloid progenitors (EMPs) that are born in the yolk sac. A first wave of EMPs ...
Yolk sac erythromyeloid progenitors sustain erythropoiesis throughout embryonic lifedoi:10.1101/2020.02.27.968230Francisca Soares-da-SilvaOdile Burlen-DefranouxRamy ElsaidLorea IturriLaina FreyerOdile SismeiroPerpétua Pinto-do-Elisa Gomez-PerdigueroAna Cumano...
Here we show, using a combination of gene expression analyses, prospective isolation approaches, transplantation, and in vivo lineage-tracing experiments, that definitive hematopoiesis initiates through committed erythromyeloid progenitors (EMPs) in the posterior blood island (PBI) that arise independently ...