20 The spectrum coverage of ceftolozane against Gram-positive and Gram-negative bacteria is generally comparable to that of third- and fourth-generation cephalosporins, but with improved anti-Pseudomonal activity. Combining ceftolozane (4) with the BLI tazobactam (5) further improves its spectrum to ...
We evaluated the effect of replacing imipenem with the group 1 carbapenem ertapenem in patients who did not require coverage. Our tertiary-level 200-bed hospital mandated use of ertapenem for infections caused by ESBL-producing Enterobacteriaceae in the absence of co-infection with non-fermenting ...
Ideally, empiric treatment should be broad spectrum in coverage, simplistic in use, and economically reasonable for the patient and the health care system. This article retrospectively reviewed the outcomes of 230 patients, 159 (69.13%) of whom were diabetic, who were admitted with lower extremity...
postpartum management of chorioamnionitis after cesarean delivery: (1) No antibiotics; (2) a one-time intravenous dose of ampicillin, gentamicin, and clindamycin (AGC-1); (3) 24-hour coverage with intravenous ampicillin, gentamicin, and clindamycin (AGC-24); (4) intravenous ertapenem, 1 dose...
These include stability in 24-h infusion pumps, broad-spectrum coverage in the empirical treatment of community-acquired pneumonia, cost, the need for effective oral agents and rare reports of emerging resistance. This study aimed to examine the in vitro susceptibility of B. pseudomallei to four ...
Poster 30 Late Post-Traumatic Seizure Associated with Ertapenem Treatment in a 19-Year-Old Woman with TBI: A Case Reportdoi:10.1016/j.pmrj.2012.09.660HenryKohAdamS.TenfordeRobertaY.WangSDOSPm & R
coli, with 92% of strains lacking full contig coverage of ompC. Overall, our findings characterize both collaborative and independent efforts between blaCTX-M and OmpC in ErMs strains, indicating the need to reappraise the term "non-carbapenemase (NCP)", particularly for strains highly expressing...
coli, with 92% of strains lacking full contig coverage of ompC. Overall, our findings characterize both collaborative and independent efforts between blaCTX-M and OmpC in ErMs strains, indicating the need to reappraise the term "non-carbapenemase (NCP)", particularly for strains highly expressing...
Treatment regimens must provide broad-spectrum coverage, including Gram-positive and Gram-negative aerobic and anaerobic bacteria of gastrointestinal origin. Ertapenem is a long-acting 1-β-methyl parenteral group 1 carbapenem antibiotic that has a broad antibacterial spectrum and once-daily dosing ...
Investigators retained the option to administer vancomycin to patients in either group to ensure adequate coverage for potentially antibiotic resistant Enterococcus spp and meticillin-resistant Staphylococcus aureus (MRSA). Our primary outcome was the proportion of patients with a favourable clinical response...