Impact of Ertapenem Use on Pseudomonas aeruginosa Susceptibility to ImipenemOveruse of group 2 carbapenems may impact resistance. We evaluated the effect of replacing imipenem with the group 1 carbapenem ertapenem in patients who did not require coverage. Our tertiary-level 200-bed hospital mandated ...
22,23 Unfortunately, their Pseudomonas coverage is poor, especially against MDR strains. In 2013, a series of cephalosporin derivatives bearing imidazolium groups at the C-3′ position were disclosed.24 An exemplified compound 8 displayed excellent broad spectrum activity encompassing Gram-positive ...