Thiery JP. Epithelial-mesenchymal transitions in tumor progression. Nat Rev Cancer. 2002;2:442-54.Prieto-Garc´ia, E., D´iaz-Garc´ia, C. V., Garc´ia-Ruiz, I., and Agullo´-Ortuno, M. T. (2017) Epithelial-to-mesenchymal transition in tumor progression. Med. Oncol. 34, ...
上皮间质转化(Epithelial-Mesenchymal Transitions,EMT)是指上皮细胞在形态学上发生成纤维细胞或间充质细胞表型的转变,并获得迁移能力,它是一种基本的生理病理现象,在胚胎发育、组织发生中起重要作用。 2. Objective To investigate the significance of pancreatic cancer cells resistance to chemoradiotherapy induces EMT...
Epithelial-to-Mesenchymal Transitions modulate interactions between Circulating Tumor Cells and the coagulation system: implication for the metastatic spread. Epithelial-Mesenchymal Transitions (EMTs) are high-profile in the field of circulating tumor cells (CTCs). EMT-shifted CTCs are considered to encomp...
The most prominent change in E-cadherin expression is seen in basal layers of the epithelium, adjacent to the basement membrane suggesting that transitions to the mesenchymal phenotype occur in epithelial cells at or near the basement membrane. In addition to changes at the basal layer, gingival ...
Bolos V, Peinado H, Perez-Moreno MA, Fraga MF, Esteller M, Cano A: The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J Cell Sci. 2003, 116: 499-511. 10.1242/jcs.00224. Article CAS...
Epithelial-to-mesenchymal transition (EMT) triggers cell plasticity in embryonic development, adult injured tissues and cancer. Combining the analysis of EMT in cell lines, embryonic neural crest and mouse models of renal fibrosis and breast cancer, we find that there is not a cancer-specific EMT...
A. Epithelial-mesenchymal transitions in development and disease. Cell 139, 871–890 (2009). Article CAS PubMed Google Scholar Kalluri, R. & Weinberg, R. A. The basics of epithelial-mesenchymal transition. J. Clin. Invest. 119, 1420–1428 (2009). Article CAS PubMed PubMed Central ...
Thiery JP, Acloque H, Huang RYJ, Nieto MA (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139(5): 871–890. Uyttenhove C, Pilotte L, Theate I, Stroobant V, Colau D, Parmentier N, Boot T, Van den Eynde BJ (2003) Evidence for a tumoral immune resistance...
Epithelial-to-mesenchymal transition (EMT) is a complex process involving multiple genes, steps and stages. It refers to the disruption of tight intercellular junctions among epithelial cells under specific conditions, resulting in loss of the original p
Epithelial—Mesenchymal and mesenchymal—Epithelial transitions in carcinoma progression. J. Cell. Physiol. 2007, 213, 374–383. [CrossRef] [PubMed] 20. Nieto, M.A. Epithelial plasticity: A common theme in embryonic and cancer cells. Science 2013, 342, 1234850. [CrossRef] [PubMed] 21. ...