Squamous epithelial cellsline the distal third of the urethra, the vagina, and the prepuce and are usually not considered significant. It is useful to note that squamous epithelial cells are the largest cell from the patient found in the urine sediment. They are flat or rolled cells that hav...
They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand for 12 population doublings in Epithelial Cell Growth Medium (Cat# MD-0041) under the condition suggested by iXCells Biotechnologies. Product Details Tissue Human adult kidney Package Size 0.5...
Human renal proximal tubular epithelial cells (HRPTEpC) play a crucial role in renal function. They reabsorb nearly all of the glucose and amino acids in the glomerular filtrate, while allowing other substances of no nutritional value to be excreted in the urine. HRPTEpC are located near i...
A total of 291 urine sediments from 255 patients with various renal or urinary tract diseases have been studied by phase contrast microscopy. Based upon morphological criteria, leucocytes were distinguished from renal epithelial cells and the white blood cells were classified either as mononuclear or ...
The mechanisms driving the development of extracapillary lesions in focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN) remain poorly understood. A key question is how parietal epithelial cells (PECs) invade glomerular capil
The assessment of endocytosis by glomerular epithelial cells was performed on 1-micron sections by counting HRP.PL grains in the GEC and expressing this in terms of the area of glomerulus examined. The results were compared to those found in normal rats. Our results show that GEC endocytotic ...
Recruitment of neutrophils and increased uroepithelial cell apoptosis results in exfoliation of infected uroepithelial cells into the urine thereby decreasing bacteria burden and the risk for re- infection.10–13 While UTI is clearly multifactorial in nature,14 genetic variability in the host may ...
The expression of Snail, a key transcriptional factor that has been implicated in initiating epithelial-to-mesenchymal transition, was induced by TGF-β1, and ectopic expression of Snail suppressed P-cadherin and nephrin in podocytes. In vivo, in addition to loss of nephrin and zonula occludens-...
Interstitial cystitis (IC) is a chronic urinary tract disease that is characterized by unpleasant sensations, such as persistent pelvic pain, in the absence of infection or other identifiable causes. We previously performed comprehensive metabolomics profiling of urine samples from IC patients using nucle...
One day before the transient transfection with Lifopecta- mine2000, the T24 cells in the logarithmic growth phase were seeded into a 12-well plate at the concentration of 1 × 105 ml−1. When the confluence reached 50–70%, the cells were added with 800 μl serum- free medium and ...