Sen P, Shah PP, Nativio R, Berger SL. 2016. Epigenetic mechanisms of longevity and aging. Cell 166:822-839. DOI: https://doi.org/10.1016/j.cell.2016.07.050, PMID: 27518561Sen P, Shah PP, Nativio R, Berger SL. Epigenetic Mechanisms of Longevity...
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It has long been assumed that lifespan and healthspan correlate strongly, yet the two can be clearly dissociated1–6. Although there has been a global increase in human life expectancy, increasing longevity is rarely accompanied by an extended healthspan
L. Epigenetic mechanisms of longevity and aging. Cell 166, 822–839 (2016). Article CAS PubMed PubMed Central Google Scholar Benayoun, B. A., Pollina, E. A. & Brunet, A. Epigenetic regulation of ageing: linking environmental inputs to genomic stability. Nat. Rev. Mol. Cell Biol. ...
Epigenetic mechanisms of longevity and aging Cell, 166 (2016), pp. 822-839 View PDFView articleView in ScopusGoogle Scholar [11] B.L.J. Kaczmarek Current views on neuroplasticity: what is new and what is old? Acta Neuropsychologica, 18 (2020), pp. 1-14 CrossrefView in ScopusGoogle Sch...
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However, while genetic, dietary and drug interventions can extend lifespan, their impact on the epigenome is uncharacterised. To fill this knowledge gap, we defined age-associated DNA methylation changes at the whole-genome, single-nucleotide level in mouse liver and tested the impact of longevity...
L. Epigenetic Mechanisms of Longevity and Aging. Cell.166, 822–839 (2016). Article CAS Google Scholar Li, Q., Ma, Y., Zhu, Y., Zhang, T. & Zhou, Y. Declined Expression of Histone Deacetylase 6 Contributes to Periodontal Ligament Stem Cell Aging. J Periodontol.26, 1–22 (2016)....
L. Epigenetic mechanisms of longevity and aging. Cell 166, 822–839. https://doi.org/10.1016/j.cell.2016.07.050 (2016). Article CAS PubMed PubMed Central Google Scholar Zhang, W., Qu, J., Liu, G. H. & Belmonte, J. C. I. The ageing epigenome and its rejuvenation. Nat. Rev....