Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. Lancet Neurol. 2009; 8:1056-1072. [PubMed: 19833297]Urdinguio RG, Sanchez-Mut JV, Esteller M. Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. Lancet Neurol 2009; 8: 1056-72....
Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. Lancet Neurol 8: 1056–1072. REVIEW Vezzani A, French J, Bartfai T, Baram TZ (2011). The role of inflammation in epilepsy. Nat Rev Neurol 7: 31–40. Wang B, Zhu X, Kim Y, Li J, Huang S, Saleem S ...
Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. Lancet Neurol. 8, 1056–1072 (2009). CAS PubMed Google Scholar Hite, K.C., Adams, V.H. & Hansen, J.C. Recent advances in MeCP2 structure and function. Biochem. Cell Biol. 87, 219–227 (2009). CAS ...
Furthermore, the epigenetic mechanisms have been shown to be altered by several factors such as lifestyle, infection, genetic and metabolic alterations, as well as other maternal factors, contributing to the neurological disorders in the offspring [15–18]. This review will br...
Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies Lancet Neurol., 8 (2009), pp. 1056-1072 Google Scholar [17] G. Sadri-Vakili, J.H. Cha Mechanisms of disease: histone modifications in Huntington's disease Nat. Clin. Pract. Neurol., 2 (2006), pp. 330-338 ...
Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. Lancet Neurol. 2009;8:1056–72. Article CAS PubMed Google Scholar Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl...
The high complexity of the nervous system means it is very sensitive to epigenetic disturbances, whereby the consequence could be reflected in neurological disorders such as Rett syndrome (RTT), Rubinstein-Taybi syndrome (RTS), Fragile X syndrome, or Alzheimer’s disease. References 1. Cognitive ...
The study of epigenetic states in neurodegenerative diseases presents an opportunity to gain new insights into risk factors and pathogenic mechanisms. Moreover, research into epigenetic regulation of disease may revolutionize health care by opening new avenues of personalized, preventive and curative ...
Epigenetic mechanisms in neurological disease. Nat Med 2012; 18: 1194–1204. Article CAS PubMed PubMed Central Google Scholar Alisch RS, Wang T, Chopra P, Visootsak J, Conneely KN, Warren ST . Genome-wide analysis validates aberrant methylation in fragile X syndrome is specific to the ...
molecular mechanisms of pathogenesis opens clear and promising avenues for the future of PD research. Carefully designed epidemiological studies carried out in PD patients hold great potential to uncover disease-relevant gene regulatory mechanisms. Therefore, to advance this burgeoning field, we recommend ...