Magni, G., Amici, A., Emanuelli, M., Raffaelli, N. & Ruggieri, S. (1999). Enzymology of NAD+ synthesis. Adv Enzymol Relat Areas Mol Biol 73, 135-182, xi.Magni, G., Amici, A., Emanuelli, M. and Raffaelli, N: Enzymology of NAD+ synthesis. In: Advances in Enzymology and ...
Electrogenic Binding of Intracellular Cations Defines a Kinetic Decision Point in the Transport Cycle of the Human Serotonin Transporter Peter S. Hasenhuetl, Michael Freissmuth, Walter SandtnerDecember 2016 Pages 25864-25876 View PDF Article preview select article Mechanism of Sirt1 NAD+-dependent ...
Because the cellular redox status depends on both the absolute concentration of pyridine dinucleotides and their respective ratios of oxidized and reduced forms (i.e., NAD/NADH and NADP/NADPH), it is conceivable that an altered regulation of the synthesis and degradation of NAD impairs the cell ...
Glutamine provides nitrogen for the synthesis of N 3 and N 9 of the purine ring, the amide nitrogen atoms of asparagine and NAD, the amino groups of glucosamine 6-phosphate, guanine, cytidine, and (as carbamyl phosphate) N 1 of the pyrimidine ring. The synthesis of glutamine is a ...
Ferguson AR, Sims AP (1971) Inactivation in vivo of glutamine synthetase and NAD-specific glutamate dehydrogenase: its role in the regulation of glutamine synthesis in yeasts. J Gen Microbiol 69: 423–427 ArticlePubMedCASGoogle Scholar Finlay RD, Frostegard A, Sonnerfeldt AN (1992) Utilization ...
The presentation encompasses all the reactions starting from the de novo pyridine ring formation and leading to nicotinamide adenine dinucleotide (NAD+) synthesis and utilization. The regulation of NAD+ homeostasis with respect to the physiological role played by the enzymes both utilizing NAD+ through...
A novel A-ring pyrazole steroid, 2,3-bisaza-A-nor-1,5(10)-estradien-17β-ol (3), was synthesized as a potential inhibitor of steroidal NAD(P)H-dependent oxidoreductases. Compound 3 proved to be a potent inhibitor of 3(17)β-hydroxysteroid dehydrogenase (from P. testosteroni) ...
Glutamine provides nitrogen for the synthesis of N 3 and N 9 of the purine ring, the amide nitrogen atoms of asparagine and NAD, the amino groups of glucosamine 6-phosphate, guanine, cytidine, and (as carbamyl phosphate) N 1 of the pyrimidine ring. The synthesis of glutamine is a ...