5alpha-reductase type 3 enzyme in benign and malignant prostate. Prostate 2014;74:235-49.Titus MA, Li Y, Kozyreva OG, Maher V, Godoy A, Smith GJ, Mohler JL (2013) 5α-reductase type 3 enzyme in benign and malignant prostate. Prostate. : 10.1002/pros.22745 Central...
3β-HSD: 3β-hydroxysteroid dehydrogenase; 5αR: 5α-reductase; 3α-HSD: 3α-hydroxysteroid dehydrogenase. Values represent mean ± SEM for each group (n = 10). *Po0.05, compared to non-sleep deprived (NSD) rats. indomethacin (5 mg/kg, IP) reduced startle magnitude in NSD rats (Po...
The relative abundance and physiological role of 5α-reductase (5αR) isoforms in rat testis, in particular 5α-reductase Type 2 (5αR2) are poorly understood. Investigation of 5αR2 activity using enzyme kinetic studies was hampered by the high concentrations of 5α-reductase Type 1 (5α...
5-alpha reductase (5AR) enzyme is a significant drug target for prostate cancer. Identification of drug targets and their inhibitors are a challenging task in drug designing. The prediction of potential inhibitors against 5AR may help in designing effective drugs against prostate cancer. Methods: ...
SYNERGIC PHARMACEUTICAL COMPOSITIONS CONSISTING OF A COMBINATION OF A 5 alpha-REDUCTASE ENZYME INHIBITOR AND A 1 alpha- ADRENERGIC RECEPTOR ANTAGONISTGarcía, Armenta María ElenaSantos Murillo, JosefinaAlvarez Ochoa, Victor Guillermo
A. Cerbón. 1999 . Modified expression of steroid 5-α reductase as well as aromatase, but not cholesterol side-chain cleaveage enzyme, in the reproductive system of male mice during ( Taenia crassiceps ) cysticercosis. Parasitology Research 85: 393 – 398 . , ,...
Steroid 5 alpha-reductase 2 deficiency: virilization in early infancy may be due to partial function of mutant enzyme. Male pseudohermaphroditism due to steroid 5 alpha-reductase deficiency is the consequence of mutations in the gene encoding the type 2 isoenzyme. Most (60%... Forti,Falchetti,...
SNA-4606-1, a new member of elaiophylins with enzyme inhibition activity against testosterone 5 alpha-reductase. Nakakoshi M,Kimura K,Nakajima N,et al.SNA-4606-1, a new member of elaiophylins with enzyme inhibition activity against testosterone 5 alpha-reductase... M Nakakoshi,KI Kimura...
SNA-4606-1, a New Member of Elaiophylins with Enzyme Inhibition Activity Against Testosterone 5.ALPHA.-Reductase. M Nakakoshi,KI Kimura,N Nakajima,... - 《Journal of Antibiotics》 被引量: 0发表: 1999年 ChemInform Abstract: SNA06 a New Member of Elaiophylins with Enzyme Inhibition ...
Factors Controlling the Expression of 5α-Reductase in Human Prostate: A Possible New Approach for the Treatment of Prostate Cancer this enzyme expressed in the prostate and recent studies have demonstrated that the type II isoenzyme is the one most affected by the onset of neoplasia... FK Habib...