Anion–π interactions occur on the surface of π-acidic aromatic planes with positive quadrupole moments. Their ability to contribute to the binding and transport of anions has been demonstrated recently. However, their ability to stabilize anionic reactive intermediates and transition states remains ess...
Square-planar cobalt(II) systems have emerged as powerful carbene transfer catalysts for the synthesis of numerous (hetero)cyclic compounds via cobalt(III)–carbene radical intermediates. Spectroscopic detection and characterization of reactive carbene r
Under homoenolization conditions (t-BuO, t-BuOH, 185 掳C), 7,7-dimethyltricyclo[3.2.1.02,4]octan-6-one (5) readily rearranges to 4,4-dimethyltricyclo[3.3.0.02,8]octan-3-one (6) which subsequently suffers reduction of the three-membered ring, presumably by electron transfer from the ...
摘要: The interaction of tris(β-ketoenolato)cobalt(III) complexes with protic acids results in a ligand–metal electron transfer with the formation of a variety of β-ketoenolyl radicals that can be detected by ESR spectroscopy.关键词: intermediates (and their reactions ...
The key intermediate (±)-2 is synthesized from 2-bromobenzaldehyde via i) dimethylacetalization, ii) Br/Li exchange and subsequent addition of 1-benzylpiperidin-4-one, iii) H+-catalyzed isobenzofuran formation, iv) tandem Wittig-Michael reaction, and v) ester reduction to 2. The synthetic ...
Introduction Enolates are a very powerful synthetic tool for the formation of highly electron-rich carbon atoms that can serve as nucleophiles. Unlike a Grignard or other organometallic reagents, however, enolate reactions are not air- or water-sensitive and therefore can be conducted under ...