[Enkephalins and the function of the sympathetic-adrenal system in acute myocardial ischemia]enkephalinscatecholaminesacute myocardial ischemiaIt has been shown in experiments on albino rats that acute myocardial ischemia (AMI) produces a noticeable increase in excretion of adrenaline, noradrenaline, DOPA ...
To provide insight into enkephalin function we used a chronic social defeat stress paradigm, where animals are either categorized as susceptible or resilient to stress based on their performance in a social interaction test. Compared to controls, susceptible animals showed reduced enkephalin levels in ...
It is now clear that there are at least three different families of endogenous opioid peptides, the enkephalins, endorphins and dynorphins. These peptides may function as neurotransmitters, neurohormones or hormones. In addition the receptor-mediated actions of these opioid peptides show a considerab...
Various enkeplalins (ENK) have been reported to alter heart rate, systemic blood pressure, and respiratory function but with variable results. We previously found that pentobarbital anesthesia reversed the increases in heart rate and systemic arterial blood pressure produced by Leu 5-ENK in the dog...
Cardiac enkephalins attenuate vagal bradycardia: interactions with NOS-1-cGMP systems in canine sinoatrial node.Endogenous opioids and nitric oxide (NO) are recognized modulators of cardiac function. Enkephalins and inhibitors of NO synthase (NOS) both produce similar interruptions in the vagal control ...
To achieve their biological function, they must be transported from an aqueous phase to the lipid-ric... S Liu,A Shibata,S Ueno,... - 《Colloids & Surfaces B Biointerfaces》 被引量: 24发表: 2006年 Adhesion forces measured between a calcium blocker drug and its receptor in living cells ...
Several lines of investigation point to the possibility that enkephalins may function as neuromodulator/neurotransmitter agents in the mammalian central nervous system. In this study we report on the release of met- and leu-enkephalin immunoreactivity from rat striatal slices in vitro and on the ...
Raman spectral studies are carried out on Leu- and Met-enkephalin as a function of the pH value in the range of 1-13. The molecules are dissolved in KCl solvent and the pH is controlled at each value. Spectral analyses reveal the dependence of the structural conformation on the pH, and ...
Data are also obtained indicating that enkephalins function as hydrogen donors for mammalian peroxidases.doi:10.1016/0006-291X(91)91347-FM.A. RoseiC BlarzinoC FoppoliR CocciaC De MarcoBiochem Biophys Res CommunRosei MA, Blarzino C, Foppoli C, Coccia R, De Marco C (1991a) The peroxidase- ...
It is suggested that methionine enkephalin could have a significant influence in enhancing cell-mediated immunity and T-cell function, particularly in lymphoma patients.doi:10.1016/0090-1229(83)90131-9G C MillerA.J. MurgoN P PlotnikoffElsevier Inc.Clinical Immunology and Immunopathology...